The Chinese University of Hong Kong & Prince of Wales Hospital

Department of Obstetrics and Gynaecology
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Prof. Wong Yick Fu

Prof. Wong Yick Fu Professor (honorary)
(852) 3505 2804 yickfuwong@cuhk.edu.hk

Qualifications

MD, PhD

1
Genomic alterations associated with mutational signatures, DNA damage repair and chromatin remodeling pathways in cervical carcinoma Halle MK , Sundaresan A, Zhang J, Pedamallu CS, Srinivasasainagendra V, Blair J, Brooke D, Bertelsen BI, Woie K, Shrestha S, Tiwari H, Wong YF, Krakstad C, Ojesina AI npj Genomic Medicine 2021 Oct; 6:82
2
Maternal Plasma RNA Sequencing for Genome-wide Transcriptomic Profiling and Identification of Pregnancy-associated Transcripts . Tsui NBY, Jiang PY, Wong YF, Leung TY, Chan AKC, Chiu RWK, Sun H, Lo DYM Clin Chem 2014;60(7): 954 - 962
3
Dysregulated microRNAs in the Pathogenesis and Progression of Cervical Neoplasm. Cheung TH, Man MKN, Yu MMY, Yim SF, Siu NSS, Lo KWK, Doran G, Wong RRY, Wang VW, Smith DI, Worley MJJR, Berkowitz RS, Chung TKH, Wong YF Cell Cycle 2012;11(15): 2876 - 2884
4
Frequent Somatic Demethylation of RAPGEF1/C3G Intronic Sequences in Gastrointestinal and Gynecological Cancer. Samuelsson J, Alonso S, Ruiz-Larroya T, Cheung TH, Wong YF, Perucho M Int J Oncol 2011;38(6): 1575 - 1577
5
Development of a Postnatal 3-day-old Rat Model of Mild Hypoxic-Ischemic Brain Injury. Stadlin A, James AE, Fiscus RR, Wong YF, Rogers MS, Haines CJ Brain Res 2003;993(1-2): 101 - 110
6
Expression Genomics of Cervical Cancer: Molecular Classification and Prediction of Radiotherapy Response by DNA Microarray. Wong YF, Selvanayagam ZE, Wei N, Porter J, Vittal R, Hu R, Yap SF, Kita T, Lin AW, Cheung TH, Lo KWK, Yim SF, Yip SK, Leung TN, Siu NSS, Chan LKY, Chan CS, Kong T, Kutlina E, McKinnon RD, Denhardt DT, Chin KV, Chung TKH Clin Cancer Res 2003;9(15): 5486 - 5492
7
Integrations of the hepatitis B virus (HBV) and human papillomavirus (HPV) into the human telomerase reverse transcriptase (hTERT) gene in liver and cervical cancers. Ferber MJ, Montoya DP, Yu C, Aderca I, McGee A, Thorland EC, Nagorney DM, Gostout BS, Burgart LJ, Boix L, Bruix J, McMahon BJ, Cheung TH, Chung TKH, Wong YF, Smith DI, Roberts LR Oncogene 2003;22(24): 3813 - 3820
8
The role of microsatellite instability in cervical intraepithelial neoplasia and squamous cell carcinoma of the cervix. Wong YF, Cheung TH, Poon KY, Wang VW, Li JCB, Lo KWK, Yim SF, Yu MMY, Lahr G, Chung TKH Gynecol Oncol 2003;89(3): 434 - 439
9
Apotosis-Related Proteins in Cervical Intraepithelial Neoplasia and Squamous Cell Carcinoma of the Cervix. Cheung TH, Chung TKH, Lo KWK, Yu MMY, Krajewski S, Reed JC, Wong YF Gynecol Oncol 2002;86(1): 14 - 18
10
Aberrant expression of p21WAF1/CIP1 and p27KIP1 in cervical carcinoma. Cheung TH, Lo KWK, Yu MMY, Yim SF, Poon CS, Chung TKH, Wong YF Cancer Lett 2001;172(1): 93 - 98
11
Alteration of cyclin D1 and CDK4 gene in carcinoma of uterine cervix. Cheung TH, Yu MMY, Lo KWK, Yim SF, Chung TKH, Wong YF Cancer Lett 2001;166(2): 199 - 206
12
Clinical and Prognostic Significance of Human Papillomavirus in Chinese Population of Cervical Cancers. Lo KWK, Cheung TH, Chung TKH, Wang VW, Poon JS, Lam PKW, Wong YF Gynecol Obstet Inves 2001;51(3): 202 - 207
13
Microsatellite instability in cervical carcinoma. Chung TKH, IP TY, Hampton GM, Wang VW, Cheung TH, Wong YF Eur J Obstet Gyn R B 2001;94(1): 121 - 124
14
Analytical survey. (Chinese Article) Rogers MS, Wong YF, Chang AMZ Chin J Prac Gynecol Obstet 2000;16(4): 249 - 250
15
Case studies (Chinese Article) Tam WH, Wong YF, Chang AMZ Chin J Prac Gynecol Obstet 2000;16(2): 112
16
Clinical research in Obstetrics & Gynaecology. (Chinese Article) Chung TKH, Chang AMZ, Wong YF Chin J Prac Gynecol Obstet 2000;16(1): 59
17
Clinical trial. (Chinese Article) Lau TK, Wong YF, Chang AMZ Chin J Prac Gynecol Obstet 2000;16(5): 313 - 314
18
Loss of Heterozygosity at the short arm of chromosome 3 in microdissected cervical intraepithelial neoplasia. Chung TKH, Cheung TH, Lo KWK, Yu MMY, Hampton GM, Wong HKT, Wong YF Cancer Lett 2000;154(2): 189 - 194
19
Overexpression of p53 and HER-2/neu and c-myc in Primary Fallopian Tube Carcinoma. Chung TKH, Cheung TH, To KF, Wong YF Gynecol Obstet Inves 2000;49(1): 47 - 51
20
p53 Polymorphism and Human Papillomavirus Infection in Hong Kong Women with Cervical Cancer. Wong YF, Chung TKH, Cheung TH, Nobori T, Hampton GM, Wang VW, Li YF, Chang AMZ Gynecol Obstet Inves 2000;50(1): 60 - 63
21
The Concept and Design of Medical Survey (Chinese Article). Sahota DS, Yuen PM, Wong YF, Chang AMZ Chin J Prac Gynecol Obstet 2000;16(3): 185 - 186
22
Clinical and pathologic significance of microsatellite instability in endometrial cancer. Wong YF, IP TY, Chung TKH, Cheung TH, Hampton GM, Wang VW, Chang AMZ Int J Gynecol Cancer 1999;9: 406 - 410
23
Clinical Use of Serum c-erbB-2 in Patients with Ovarian Masses. Cheung TH, Wong YF, Chung TKH, Maimonis P, Chang AMZ Gynecol Obstet Inves 1999;48(2): 133 - 137
24
Expression of p16INK4 and retinoblastoma protein Rb in vulvar lesions of Chinese women. Chan KMM, Cheung TH, Chung TKH, Bao SY, Nobori T, Wong YF Gynecol Oncol 1998;68: 156 - 161
25
MTAP gene deletion in endometrial cancer. Wong YF, Chung TKH, Cheung TH, Nobori T, Chang AMZ Gynecol Obstet Inves 1998;45: 272 - 276
26
Uterine sarcoma and bilateral renal angiomyolipomas. Yang WT, Leung TN, Metreweli C J H K College Radiologists 1998;1(2): 141 - 143
27
c-fos Overexpression Is Associated with the Pathoneogenesis of Invasive Cervical Cancer. Cheung TH, Leung JO, Chung TKH, Lam SK, To KF, Wong YF Gynecol Obstet Inves 1997;43(3): 200 - 203
28
Expression of p16INK4 and Rb Genes in Cervical Neoplasm. Wong YF, Cheung TH, Chung TKH, Chan MKM, Chang AMZ J Lower Genital Tract Disease 1997;1(4): 240 - 244
29
Frequent Loss of Heterozygosity of Chromosome 3 Short Arm Detected by PCR-based Microsatellite Polymorhisms in Cervical Squamous Cell Carcinoma. Wong YF, Chung TKH, Cheung TH, Tam POS, Chang AMZ Cancer Lett 1997;115: 161 - 164
30
Prediction and prevention of perinatal morbidity in Hong Kong. (Chinese Article) Rogers MS, Wong YF Chin J Obstet Gynecol 1997;32: 393 - 395
31
Research in the menopause in Hong Kong. (Chinese Article) Chung TKH, Haines CJ, Wong YF Chin J Obstet Gynecol 1997;32: 5 - 7
32
電視腹腔鏡術在子宮內膜異位症診治的應用 Yuen PM, Wong YF Chin J Prac Gynecol Obstet 1997;13(6): 329 - 330
33
C-myc mutation detected by polymerase chain reaction - heteroduplex in cervical cancer. Wong YF, Rogers MS, Cheung TH, Yim SF, Chang AMZ Gynecol Obstet Inves 1997;44(2): 136 - 140
34
Allelic imbalance of chromosome 3 short arm in cervical cancer. (Chinese Article) Wong YF, Chang AMZ Chin Prac J Gynecol Obstet 1996;12(6): 343 - 344
35
Coincidental renal cell and endometrial carcinoma. Lam SK, Chung TKH, Mackenzie TM, To KF, Wong YF, Cheung TH, Chang AMZ Gynecol Oncol 1996;60(2): 319 - 324
36
Cytogenetic analysis of gynecologic malignancies. (Chinese Article) Wong YF, Wang VW, Wong FWS, Chang AMZ Chin J Prac Gynecol Obstet 1996;9(2): 106
37
HER-2/neu gene amplication in cervical cancer in Chinese women of Hong Kong and China. Wong YF, Chung TKH, Cheung TH, Lam SK, Chang AMZ, Tam POS, Xu FD, Lu HJ J Obstet Gynaecol Res 1996;22(2): 171 - 175
38
Molecular detection of human papillomavirus and H-ras codon 12 mutation in cervical carcinoma patients from Hong Kong. Li LM, Kwong YYD, Cheung TH, Chung TKH, Lam SK, Wong YF J Genet Mol Biol 1996;7(4): 55 - 60
39
New approach on gynaecological oncology. Lam SK, Wong YF Pract.J.Gynecol.Obstet. 1996;12: 121 - 122
40
Progress in obstetrics. (Chinese Article) Wong YF Reprod Contracept 1996;9: 25 - 29
41
Serum lipid-assocciated sialic acid levels in gynecologic malignancies. Wong YF, Wong FWS, Neale EJ Int J Gynecol Cancer 1996;3: 143 - 146
42
Detection of fetal Y-specific DNA from the cervix. Fung HYM, Wong YF, Haines CJ, Wong FWS Acta Obstet Gyn Scan 1995;74(4): 248 - 250
43
Frequent ras gene mutations in squamous cell cervical cancer. Wong YF, Chung TKH, Cheung TH, Lam SK, Chang AMZ, Xu YG Cancer Lett 1995;95(1): 29 - 32
44
Prevalence and significance of HER-2/neu amplification in epithelial ovarian cancer. Wong YF, Cheung TH, Lam SK, Lu HJ, Zhuang YL, Chan MYM, Chung TKH Gynecol Obstet Inves 1995;40(3): 209 - 212
45
Progress in diagnosis and treatment of trophoblastic disease. (Chinese Article) Wong YF Chin J Prac Gynecol Obstet 1995;11: 117 - 118
46
Present diagnosis and treatment of gynaecologic cancers. 婦科腫瘤的診治現狀 Lam SK, Cheung TH, Wong YF Pract.J.Gynecol.Obstet. 1995;11(4): 238
47
Effect of human papilloma type specific antisense oligonucleotides on cervical cancer cells containing papillomavirus type 16. Chung TKH, Chang AMZ, Wong YF, Cheung TH, Cheung LP Med Oncol 1994;11: 149 - 151
48
Ki67 and AgNOR staining in squamous cell carcinoma of the cervix: a comparison. Chung TKH, Cheung TH, Wong FWS, Wong YF Gynecol Obstet Inves 1994;37(2): 127 - 129
49
Progress in diagnosis and treatment of ovarian cancer. Wong YF Pract.J.Gynecol.Obstet. 1994;10: 115 - 116
50
Cytogenetic analysis of gynecologic malignancies. Wong YF, Wong FWS, Chang AMZ, Wang VW Pract.J.Gynecol.Obstet. 1993;9: 103 - 106
51
Detection of Human Papilloma Virus (HPV) infection in paraffin-embedded tissues of endometrial carcinoma. Wong FWS, Wong YF, Tam POS, Tam JS Aust NZ J Obstet Gyn 1993;33(2): 180 - 182
52
Frequent loss of heterozygosity on the short arm of chromosome 1 in cervical carcinoma. Wong YF, Wong FWS, Cheung TH, Fung HYM, Chung TKH, Lam SK, Tam POS, Chang AMZ Med Sci Res 1993;21: 891 - 892
53
Genetic studies in gynaecological malignancies. Wong YF Pract.J.Gynecol.Obstet. 1993;9: 101 - 102
54
Human papillomavirus infections in Hong Kong women with cervical carcinoma. (Chinese Article) Wong YF, Wong FWS, Tam SL, Wang VW Chin J Cancer 1993;12: 42 - 44
55
Nucleolar organiser regions in endometrial carcinoma. Wong YF, Fung HYM, Wong FWS, Wang VW, Cheung TH, Chung TKH, Chang AMZ Med Sci Res 1993;21: 325 - 326
56
Preoperative combination assay of serum CA 125 and lipid-associated sialic acid in women with ovarian tumour. Wong YF, Wong FWS, Fung HYM, Tam POS, Wang VW, Cheung TH, Chang AMZ Med Sci Res 1993;21: 397 - 398
57
Serum lipid-assoicated sialic acid levels in gynecologic malignancies. Wong YF, Neale EJ, Wong FWS Int J Gynecol Cancer 1993;3(3): 143 - 146
58
Serum lipid-associated sialic acid levels in gynecologic malignancies. Wong YF Int J Gynecol Cancer 1993;3(3): 143 - 146
59
Answering MCQs: a study of confidence amongst medical students. Rogers MS, Chung TKH, Li A Aust NZ J Obstet Gyn 1992;32: 1 - 3
60
Argyrophilic nucleolar organizer region counts as related to Bromodeoxyuri-Dine incoroporation scores in ovarian clear cell carcinoma cells. (Chinese Article) Wong FWS, Wang VW, Wong YF, Chang AMZ Chin.J.Tumor 1992;14(2): 87 - 90
61
Chromosomal alternations in cervical carcinoma. Wang VW, Wong YF, Wong FWS, Chang AMZ Med Sci Res 1992;20: 193 - 194
62
Treatment of menopausal osteoporosis. Wong YF Abroad Med 1992;19: 70 - 71
63
A simple method of chromosome preparation from gynaecological solid tumour. Wong FWS Med Sci Res 1991;10: 705 - 706
64
Advances in diagnosis and management of cervical cancer. Wong YF Pract.J.Gynecol.Obstet. 1991;7: 331
65
Cytogenetic studies in vitro passages of an ovarian cell line. Wang VW, Wong YF, Wong FWS, Chang AMZ Med Sci Res 1991;20: 87 - 89
66
Endometrium ablation for the treatment of menorrhageia. Wong YF, Leung KL Abroad Med 1991;18: 345 - 347
67
New approach to trophoblastic diseases. Wong YF Pract.J.Gynecol.Obstet. 1991;7: 273 - 274
68
A morphological study of effects of trichosanthin on cultured choriocaricinoma. Wong YF, Chew EC, Wong FWS, Chang AMZ Med Sci Res 1990;18: 379 - 381
69
Binding of radio labelled trichosanthin with tumourcells in vitro. Wong YF, Wong FWS, Chang AMZ Med Sci Res 1990;18: 667 - 669
70
Correlation of agyrophilic nucleolar organiser regions (AgNORs) count to bromodeoxyuridine incorporation and Ki-67 scores in an ovarian carcinoma cell line. Wong FWS, Wong YF, Cheung TH Med Sci Res 1990;18: 929 - 931
71
Effects of trichosanthin on cell growth cell cycle phase distribution and macromolecule synthesis in huaman choriocarcinoma cells. Wong YF, Wong FWS, Chang AMZ Med Sci Res 1990;18: 383 - 384
72
Establishment and characterization of a new human cell line derived from ovarian clear cell carcinoma. Wong FWS, Wong YF, Ng YT, Huang PD, Chew EC, Ho TH, Chang AMZ Gynecol Oncol 1990;38(1): 37 - 45
73
Evaluation of trichosanthin against xenografts of human choriocarcinom. Wong YF, Wong FWS, Chen XG, Zeng XM, Chang AMZ Med Sci Res 1990;18: 95 - 96
74
Hormone profile in the early luteal phase of stimulatd cycles for in vitro fertilization and embryo transfer. Wong YF, Wang VW, Mao KR Reprod Contracept 1990;10: 24 - 27
75
Salivary estradiol and progesterone after in vitro fertilization and embryo transfer using different luteal support regimens. Wong YF, Loong EPL, Mao KR, Tam PPL, Panesar NS, Neale EJ, Chang AMZ Reprod Fert Develop 1990;2(4): 351 - 358
76
Salivary estradiol and progesterone during the normal ovulatory menstrual cycle. Wong YF, Mao KR, Panesar NS, Loong EPL, Chang AMZ Eur J Obstet Gyn R B 1990;34(1): 129 - 135
77
Effects of the combination of trichosanthin with adriamycin and cisplatin on cultured tumour cells. Wong YF, Wong FWS, Yeung HW, Chang AMZ Med Sci Res 1989;17: 167 - 169
78
Effects of trichosanthin protein and polysaccharide on choriocarcinoma cell in vitro. Wong YF, Wong FWS, Tian GY, Chang AMZ No Abbrev 1989;9(3): 106 - 108
79
Factors affecting the success of in vitro fertilization and embryo transfer : a survey of 209 cycles. Wong YF, Mao KR, Loong EPL, Chang AMZ Pract.J.Gynecol.Obstet. 1989;5: 143 - 146
80
Inhibitory effect of crystalline trichosanthin on the growth of tumour cells in vitro. (Chinese Article) Wong YF, Wong FWS, Yeung HW, Chang AMZ Chin J Cancer 1989;8(3): 167 - 169
81
Inhibitory effects of trichosanthin and Tian Hua Fen polysaccharide on the growth of human choriocarcinoma cells in vitro. Wong YF, Wong FWS, Yeung HW, Chang AMZ No Abbrev 1989;9: 106 - 109
82
Preliminary studies on characteristics of indomethacin release from silastic devices and its histomcompatibility with uterus. Wong YF, Jin YC Reprod Contracept 1989;9: 25 - 29
83
The cervix-ripening effect of 15-methyl-prostaglandin F2 alpha methyl ester before vacuum aspiration for termination of early pregnancy in primigravidae. Wong YF, Jin YC Chin Med J 1989;102: 200 - 205
84
Varian endodermal sinus (Yolk sac) tumour. Wong FWS, Wong YF Pract.J.Gynecol.Obstet. 1989;4: 341 - 343
85
Correlation between follicular phase plasma estradiol and luteal phase plasma progesterone in an in-vitro fertilization program. Wong YF, Tam PPL, Chan AC, Mao KR, Chiu TTY, Chang AMZ Gynecol Endocrinol Proc Annu Symp R 1988;2: 267 - 268
86
Correlation between follicular phase plasma Oestradiol and luteal phase plasma progesterone in an in vitro fertilization program. Loong EPL, Wong YF, Mao KR, Tam PPL, Chang AMZ Recent Dev Gynecol Obstet 1988;2(2): 548 - 552
87
Human papillomavirus-type 16 infection and its assoicated with cervical neoplasm in Hong Kong. Wong FWS, Wong YF Shanghai.Med.J. 1988;11: 187 - 191
88
A comparison of the transabdominal and transvaginal methods of ultrasound-guided aspiration of pre-ovulatory oocytes for in vitro fertilisation. Mao KR, Tam PPL, Loong EPL, Lee HC, Wong YF, Chiu TTY Clin Reprod Fertil 1987;5(6): 373 - 378
89
Ultrasonically guided aspiration of oocyte in in-vitro fertilization and embryo transfer. Mao KR, Wong YF, Tam PPL Shanghai.Med.J. 1987;10: 258 - 262