The selected publications  in prenatal genetic diagnosis, preterm birth, fetal growth restriction, and fetal therapy. 


Diagnostic accuracy of the BACs-on-Beads™ assay versus karyotyping for prenatal detection of chromosomal abnormalities: a retrospective consecutive case series.

Choy K, Kwok Y, Cheng Y, Wong K, Wong H, Leung K, Suen K, Adler K, Wang C, Lau T, Schermer M, Lao T, Leung TY.

BJOG 2014; 121:1245-52.


Is High Fetal Nuchal Translucency Associated with Submicroscopic Chromosomal Abnormalities by Array CGH?

Huang J, Poon LC, Akolekar R, Choy KW, Leung TY, Nicolaides KH.

Ultrasound Obstet Gynecol 2014; 43: 620-624.


Noninvasive Prenatal Molecular Karyotyping from Maternal Plasma.

Yu JCY, Jiang PY, Choy KW, Chan AKC, Won HS, Leung WC, Lau ET, Tang MHY, Leung TY, Lo DYM, Chiu RWK

PLos ONE 2013;8(4): e60968


Noninvasive Twin Zygosity Assessment and Aneuploidy Detection by Maternal Plasma DNA Sequencing.

Leung TY, Qu JZZ, Liao GJW, Jiang PY, Cheng YKY, Chan AKC, Chiu RWK, Lo DYM

Prenatal Diag 2013;33(7): 675 - 681


Noninvasive Prenatal Determination of Twin Zygosity by Maternal Plasma DNA Analysis.

Qu JZZ, Leung TY (co-1st author), Jiang P, Liao GJW, Cheng YKY, Sun H, Chiu RWK, Chan KCA, Lo YM.

Clin Chem 2013; 59:427-35.


Identification of Submicroscopic Chromosomal Aberrations in Fetuses with increased Nuchal Translucency and Apparently Normal Karyotype.

Leung TY, Vogel I, Lau TK, Chong WS, Hyett JA, Petersen OB, Choy KW

Ultrasound Obst Gyn 2011;38(3): 314 - 319


Non-Invasive Prenatal Assessment of Trisomy 21 by Multiplexed Maternal Plasma DNA Sequencing : Large Scale Validity Study.

Chiu RWK, Akolekar R, Zheng YWL, Leung TY, Sun H, Chan AKC, Lun FMF, Go ATJI, Lau ET, To WWK, Leung WC, Tang RYK, Au Yeung KC, Lam H, Kung YY, Zhang XQ, Van Vugt JMG, Minekawa R, Tang MHY, Wang J, Oudejans CBM, Lau TK, Nicolaides KH, Lo DYM

Brit Med J 2011;342: c7401


Maternal Plasma DNA Sequencing Reveals the Genome-Wide Genetic and Mutational Profile of the Fetus.

Lo DYM, Chan AKC, Sun H, Chen EZ, Jiang PY, Lun FMF, Zheng YWL, Leung TY, Lau TK, Cantor CR, Chiu RWK

Sci Transl Med 2010;2(61): 61ra91


Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma.

Chiu Rossa WK, Chan AKC, Gao Y, Lau VYM, Zheng W, Leung TY, Foo CHF, Xie B, Tsui NBY, Lun FMF, Zee BCY, Lau TK, Cantor CR, Lo DYM

Proc Natl Acad Sci USA 2008;105(51): 20458 - 20463