Overview

The Fetal Medicine Team provides a wide range of prenatal screening, diagnostic, therapeutic and counselling services to pregnant women in Hong Kong and overseas as either public and private patients.

Prenatal Screening

• Expanded Carrier Screening (ECS)
• Fragile X-screening
• First trimester Combined Down syndrome screening using Nuchal translucency and biochemical markers (OSCAR)
• First trimester Preeclampsia Screening
• Second trimester biochemical Down Syndrome Screening
• Non-invasive prenatal testing of Down syndrome using circulating cell free fetal DNA (NIPT)
• First trimester fetal morphology scan
• Second trimester Fetal morphological scan

Prenatal Diagnostic procedures

• Chorionic villus sampling
• Amniocentesis
• Cordocentesis

Fetal genetic diagnosis

• Standard Karyotyping
• Rapid testing: PCR, FISH, BoBs Assay
• Comprehensive Fetal DNA Chip (CMA) and next-generation sequencing including whole exome sequencing (WES) and whole genome sequencing (WGS)

Fetal therapy

• Fetoscopic laser photocoagulation for twin-twin transfusion syndrome or other complicated monochorionic twin pregnancies
• Selective fetocide for complicated twin pregnancies
• Intrauterine transfusion (IUT) for fetal anaemia
• Shunting for fetal pleural effusion, macrocystic congenital pulmonary airway malformation (CPAM), lower urinary tract obstruction (LUTO), etc.
• Fetoscopic Endoluminal Tracheal Occlusion (FETO) for congenital diaphragmatic hernia (CDH)
• Other therapies, such as radiofrequency ablation (RFA) for bronchopulmonary sequestration (BPS) and vascular embolization for placental chorioangioma

Genetic Counseling

• Explanation and discussion with parents for abnormal or complicated genetic test results, with guidance on the future investigation and management

Newborn Screening

• Newborn Metabolic Screening