Academic Publications in Reproductive Medicine


The identification of endometrial immune cell densities and clustering analysis in the mid-luteal phase as predictor for pregnancy outcomes after IVF-ET treatment.

Zhao Y, Man GCW, Wang J, Liu Y, Kwong J, Zhang T, Chung JPW, Wang CC, Chen X, Li TC.

J Reprod Immunol. 2021 Nov;148:103


Hyoscine butylbromide in pain reduction associated with ultrasound-guided manual vacuum aspiration: a randomized placebo-controlled trial.

Chung JPW, Law TSM, Mak JSM, Liu RCY, Sahota DS, Li TC.

Reprod Biomed Online. 2021 Oct 25:S1472-6483(21)00525-3.


Therapeutic effects of green tea on endometriosis.

Chen X, Man GCW, Hung SW, Zhang T, Fung LWY, Cheung CW, Chung JPW, Li TC, Wang CC.

Crit Rev Food Sci Nutr. 2021 Oct 7:1-14.


Ovarian reserve and recurrence 1 year post-operatively after using haemostatic sealant and bipolar diathermy for haemostasis during laparoscopic ovarian cystectomy.

Chung J, Law T, Mak J, Sahota DS, Li TC.

Reprod Biomed Online. 2021 Aug;43(2):310-31


Expanded Carrier Screening Using Next- Generation Sequencing of 123 Hong Kong Chinese families: A Pilot Study.

Chan OYM, Leung TY, Cao Y, Shi MM, Kwan AHW, Chung JPW, Choy KW, Chong SC.

Hong Kong Med J. 2021 Jun;27(1):177-183.


Pharmaceuticals targeting signaling pathways of endometriosis as potential new medical treatment:

Hung SW, Zhang R, Tan Z, Chung JPW, Zhang T, Wang CC.

A review. Med Res Rev. 2021 Jul;41(4):2489-2564.


Application of convolutional neural network on early human embryo segmentation during in vitro fertilization. Journal of cellular and molecular medicine,

Zhao M, Xu M, Li H, Alqawasmeh O, Chung JPW, Li TC, Lee T, Tang PM, Chan DYL.

2021 Mar;25(5):2633-2644


Clinical Implementation of Expanded Carrier Screening in Pregnant Women at Early Gestational Weeks:

Shi M, Liauw AL, Tong S, Zheng Y, Leung TY, Chong SC, Cao Y, Lau TK, Choy KW, Chung JPW.

A Chinese Cohort Study. Genes (Basel). 2021 Mar 29;12(4):496


Potential effects of COVID-19 on reproductive systems and fertility; assisted reproductive technology guidelines and considerations: a review.

Lee WY, Mok A, Chung JPW.

Hong Kong Med J. 2021 Apr;27(2):118-126.


Treatment of patients with mayer-rokitanskyküster-hauser syndrome in a tertiary hospital.

Ng K, Ip PNP, Yiu KW, Chung JPW, Chan SSC.

Hong Kong Med J. 2020 Oct 16


Comparison of uterine artery Doppler measurements at 6 weeks of pregnancy after IVF between pregnancies that resulted in miscarriage and ongoing pregnancies.

Guo J, Chaemsaithong P, Huang J, Chung JPW, Huang J, Poon LCY, Li TC.

Int J Gynaecol Obstet. 2020 Sep 13.


The Pregnancy Outcome of Mosaic Embryo Transfer: A Prospective Multicenter Study and Meta-Analysis.

Zhang YX, Chen JJ, Nabu S, Yeung QSY, Li Y, Tan JH, Suksalak W, Chanchamroen S, Quangkananurug W, Wong PS, Chung JPW, Choy KW.

Genes (Basel). 2020 Aug 21;11(9):E973.


Low-pass genome sequencing: a validated method in clinical cytogenetics.

Chau MHK, Wang H, Lai Y, Zhang Y, Xu F, Tang Y, Wang Y, Chen Z, Leung TY, Chung JPW, Kwok YK, Chong SC, Choy KW, Zhu Y, Xiong L, Wei W, Dong Z.

Hum Genet. 2020 May 25


Ovarian HBV replication following ovulation induction in female hepatitis B carriers undergoing IVF treatment: A prospective observational study.

Mak JSM, Lao TT, Leung MBW, Chung CHS, Chung JPW, Cheung LP, Li TC.

J Viral Hepat. 2020 Feb;27(2):110-117.


Awareness of fertility preservation among Chinese medical students.

Ng EYL, Ip JKH, Mak DR, Chan AYW, Chung JPW*.

Hong Kong Med J. 2020 Jun;26(3):184-191


External validation of a simple scoring system to predict pregnancy viability in women presenting to an early pregnancy assessment clinic.

Wan OYK, Chan SSC, Chung JPW, Kwok JWK, Lao TTH, Sahota DS.

Hong Kong Med J. 2020 Apr;26(2):102-110.


Fertility preservation in Hong Kong Chinese society: awareness, knowledge and acceptance.

Yeung SY, Ng EYL, Lao TTH, Li TC, Chung JPW*.

BMC Womens Health. 2020 Apr 29;20(1):86.


Preservation of fertility in premenopausal patients with breast cancer.

Wang SSY, Loong H, Chung JPW, Yeo W.

Hong Kong Med J. 2020 Jun;26(3):216-226.


Genome Sequencing Explores Complexity of Chromosomal Abnormalities in Recurrent Miscarriage.

Dong Z, Yan J, Xu F, Yuan J, Jiang H, Wang H, Chen H, Zhang L, Ye L, Xu J, Shi Y, Yang Z, Cao Y, Chen L, Li Q, Zhao X, Li J, Chen A, Zhang W, Wong HG, Qin Y, Zhao H, Chen Y, Li P, Ma T, Wang WJ, Kwok YK, Jiang Y, Pursley AN, Chung JPW, Hong Y, Kristiansen K, Yang H, Piña-Aguilar RE, Leung TY, Cheung SW, Morton CC, Choy KW, Chen ZJ.

Am J Hum Genet. 2019 Dec 5;105(6):1102-1111.


The effects of daily meteorological perturbation on pregnancy outcome: Follow-up of a cohort of young women undergoing IVF treatment.

Zhao M, Zhang H, Waters THB, Chung JPW, Li TC, Chan DYL.

Environ Health. 2019 Nov 28;18(1):14pages


Endometrial microbiota in infertile women with and without chronic endometritis as diagnosed using a quantitative and reference range-based method.

Liu Y, Ko EYL, Wong KKW, Chen X, Cheung WC, Law TSM, Chung JPW, Tsui SKW, Li TC, Chim SSC.

Fertil Steril. 2019 Oct; 112(4):707-717.el


A comparison of uterine natural killer cell density in the peri-implantation period between natural cycles and hormone replacement therapy cycles.

Yang WJ, Chen X, Zhao Y, Cheung WC, Hsiao SY, Liu Y, Law TSM, Chung JPW*, Li TC.

Am J Reprod Immunol. 2019 Sep;82(3):e13156.


A double-blinded, randomized placebo-controlled trial on the effect of traditional Chinese medicine formula Wuzi Yanzong pill on improving semen qualities in men with suboptimal parameters.

Zhao M, Chan CPS, Cheung CWC, Alqawasmeh O, Wang RCC, Wu JCY, Lin ZX, Li TC, Chung JPW, Mak JSM, Law TSM, Chan DYL.

Trials. 2019 Aug 29;20(1):540.


A prospective study of non-invasive preimplantation genetic testing for aneuploidies (NiPGT-A) using next-generation sequencing (NGS) on spent culture media (SCM).

Yeung QSY, Zhang YX, Chung JPW, Lui WT, Kwok YKY, Gui B, Kong GWS, Cao Y, Li TC, Choy KW.

J Assist Reprod Genet. 2019 Aug;26(8);1609-1621.


Presence of Hepatitis B virus DNA in follicular fluid in female Hepatitis B carriers and outcome of IVF/ICSI treatment: A prospective observational study.

Mak JSM, Leung MBW, Chung CHS, Chung JPW, Cheung LP, Lao TT, Li TC.

Eur J Obstet Gynecol Reprod Biol. 2019 Aug;239:11-15.


Prevalence of obstetric anal sphincter injury following vaginal delivery in primiparous women: a retrospective analysis.

Kwok SPK, Wan OYK, Cheung RYK, Lee LL, Chung JPW, Chan SSC.

Hong Kong Med J. 2019 Aug;25(4):271-8.


Reproductive outcomes after surgical treatment of asherman syndrome: A systematic review.

Guo EJ, Chung JPW, Poon LCY, Li TC.

Best Pract Res Clin Obstet Gynaecol. 2019 Aug;59:98-114.


Semiconductor Sequencing For Preimplantation Genetic Testing For Aneuploidy,

Gui BH, Zhang YX, Liang B, Kwok YKY, Lui WT, Yeung QSY, Kong LY, Xuan LM , Chung JPW, Choy KW.

J Vis Exp.2019 Aug 25; (150)


Endometrial Vascularization Characterized by Optical Coherence Tomography and Immunohistochemistry in Women Undergoing In Vitro Fertilization-Embryo Transfer Treatment.

Law TSM, Cheung WC, Wu F, Zhang R, Chung JPW, Wang CC, Chen X, Li TC.

Medicina (Kaunas). 2019 Mar 27;55(4):81.


A prospective observational study on the stress levels at the time of embryo transfer and pregnancy testing following in vitro fertilisation treatment: a comparison between women with different treatment outcomes.

Cheung C, Saravelos SH, Chan T, Sahota DS, Wang CC, Chung PW, Li TC.

BJOG. 2019 Jan;126(2):271-279.


Efficacy, feasibility and patient acceptability of ultrasound-guided manual vacuum aspiration for treating early pregnancy loss.

Chung JPW, Chung CHS, Mak JSM, Li TC, Kong GWS.

Aust N Z J Obstet Gynaecol. 2019;59(1):71-76.


Impact of haemostatic sealant versus electrocoagulation on ovarian reserve after laparoscopic ovarian cystectomy of ovarian endometriomas: a randomised controlled trial.

Chung J, Law T, Chung C, Mak J, Sahota DS, Li TC.

BJOG. 2019 Sep;126(10):1267-1275


Maternal β-HCG concentrations in early IVF pregnancy: association with the embryo development stage of blastocysts.

Zhu W, Yeung Q, Chan D, Chi L, Huang J, Wang Q, Chung J, Li TC.

Reprod Biomed Online. 2019;38(5):683-690.


Practical Considerations in Providing Preimplantation Genetic Testing for Aneuploidies (PGT-A).

Yeung QSY, Zhang YX, Chung JPW, Kwok YKY, Gui BH, Choy KW, Li TC.

Fertility & Reproduction, 2019, 1.01: 21-29.


Uterine Fibroid Symptom and Health-related Quality of Life Questionnaire: a Chinese translation and validation study.

Yeung SY, Kwok JWK, Law SM, Chung JPW, Chan SSC.

Hong Kong Med J. 2019 Dec;25(6):453-459.


Increased expression of angiogenic cytokines in CD56+ uterine natural killer cells from women with recurrent miscarriage.

Chen X, Liu Y, Cheung WC, Zhao Y, Huang J, Chung JPW, Wang CC, Li TC.

Cytokine. 2018;110:272-276.


The impact of music therapy on pain and stress reduction during oocyte retrieval – a randomized controlled trial.

Cheung CWC, Yee AWW, Chan PS, Saravelos SH, Chung JPW, Cheung, LP, Kong WSG, Li TC.

Reprod Biomed Online. 2018;37(2),145-152.


The investigation and management of adenomyosis in women who wish to improve or preserve fertility.

Li JJ, Chung JPW^, Wang S, Li TC, Duan H.

Biomed Res Int. 2018;15;2018:6832685.


Effect of mid-follicular phase recombinant LH versus urinary HCG supplementation in poor ovarian responders undergoing IVF – a prospective double-blinded randomized study.

Mak SM, Wong WY, Chung HS, Chung PW, Kong GW, Li TC, Cheung LP.

Reprod Biomed Online. 2017;34(3):258-266.


Evaluation of the awareness of, attitude to, and knowledge about fertility preservation in cancer patients among clinical practitioners in Hong Kong.

Chung JP, Lao TT, Li TC.

Hong Kong Med J. 2017;23:556-561.


The changing pattern of uterine contractions before and after fresh embryo transfer and its relation to clinical outcome.

Chung CH, Wong AW, Chan CP, Saravelos SH, Kong GW, Cheung LP, Chung JP, Li TC.

Reprod Biomed Online. 2017;34(3):240-247.


A prospective randomized controlled trial of 3D versus 2D ultrasound-guided embryo transfer in women undergoing ART treatment.

Saravelos SH, Kong GW, Chung JP, Mak JS, Chung CH, Cheung LP, Li TC.

Hum Reprod. 2016;31(10):2255-2260.


Assessment of the embryo flash position and migration with 3D ultrasound within 60 min of embryo transfer.

Saravelos SH, Wong AW, Chan CP, Kong GW, Cheung LP, Chung CH, Chung JP, Li TC.

Hum Reprod. 2016;31(3):591-596.


Fertility Preservation in Young Female Cancer Patients.

Chung JPW, Kong GWS, Li TC.

MIMS JPOG Jan-Feb 2016: 24-31


Monochorionic quadramniotic and triamniotic pregnancies following single embryo transfers: two case reports and a review of the literature.

Saravelos SH, Zhang T, Chung JP, Sun LM, Sun Y, Li TC, Chen ZJ.

J Assist Reprod Genet. 2016;33(1):27-32


Dynamic changes of DNA epigenetic marks in mouse oocytes during natural and accelerated aging.

Qian Y, Tu J, Tang NL, Kong GW, Chung JP, Chan WY, Lee TL.

Int J Biochem Cell Biol. 2015; 67:121-127.


A Randomized Crossover Study of Medroxyprogesterone Acetate and Diane-35 on Adolescent Girls with Polycystic Ovarian Syndrome.

Chung JPW, Yiu AKW, Chung TKH, Chan SSC.

J Pediatr Adolesc Gynecol. 2014;27(3):166-171.


Sperm cryopreservation for Chinese male cancer patients: a 17-year retrospective analysis in an assisted reproductive unit in Hong Kong.

Chung JP, Haines CJ, Kong GW.

Hong Kong Med J. 2013 Dec;19(6):525-530.


Hysterectomy for Recurrent Postmenopausal Bleeding Revisited: Missed Sclerosing Stromal Ovarian Tumour.

Chung JPW, Cheung ECW, Yim SF, Mak SM.

Hong Kong Med J 2012;18(4): 338 – 339.


Long‐term reproductive outcome after hysteroscopic proximal tubal cannulation–an outcome analysis.

Chung JPW, Haines CJ, Kong GWS.

Aust N Z J Obstet Gyn 2012;52(5): 470 – 475.


Development and Validation of a Novel Prognostic Nomogram Combined with Desmoplastic Reaction for Synchronous Colorectal Peritoneal Metastasis

Qin X, Zhao M, Deng W, Huang Y, Cheng Z, Chung JPW, Chen X, Yang K, Chan DYL, Wang H

Front Oncol. 2022 Mar 11;12:826830


Effects of nonoxynol-9 (N-9) on sperm functions: systematic review and meta-analysis

Xu M, Zhao M, Li RHW, Lin Z, Chung JPW, Li TC, Lee TL, Chan DYL

Reprod Fertil. 2022 Feb 21;3(1):R19-R33


Debates on Fetal Fraction Measurement and DNA-based Noninvasive Prenatal Screening: Time for Standardisation.

Wataganara T, Bui TH, Choy KW, Leung TY

BJOG Sep 2016;123(S3): 31 - 35


Accurate Description of DNA-based Noninvasive Prenatal Screening.

Cheung SW, Petal A, Leung TY

N Engl J Med 2015;372(17): 1675 - 1677


Noninvasive Prenatal Testing by Nanopore Sequencing of Maternal Plasma DNA: Feasibility Assessment.

Cheng SH, Jiang PY, Sun K, Cheng YKY, Chan AKC, Leung TY, Chiu RWK, Lo DYM

Clin Chem 2015;61(10): 1305 - 1306


Noninvasive Testing for Fetal Aneuploidy: A Hong Kong Perspective.

Sahota DS

Am. J Bioeth 2015;6(1): 106 - 110


Plasma DNA Tissue Mapping by Genome-Wide Methylation Sequencing for Noninvasive Prenatal, Cancer, and Transplantation Assessments.

Sun K, Jiang PY, Chan AKC, Wong J, Cheng YKY, Liang RHS, Chan WK, Ma ESK, Chan SL, Cheng SH, Chan RWY, Tong YK, Ng SSM, Wong RSM, Hui DSC, Leung TN, Leung TY, Lai PBS, Chiu RWK, Lo DYM

Proc Natl Acad Sci USA 2015;112(40): e5503 - e5512


Prenatal Diagnosis of 24 Cases of Microduplication 22q11.2: An Investigation of Phenotype-genotype Correlations.

Dupont C, Grati F, Choy KW, Jaillard S, Toutain J, Maurin ML, Martinez-Conejero JA, Beneteau C, Coussement A, Molinagomes D, Horelli-Kuitunen N, Aboura A, Tabet AC, Besseau-Ayasse J, Bessieres GB, Simoni G, Ayala G, Benzacken B, Vialard F

Prenatal Diag 2015;35(1): 35 - 43


Prevalence of Recurrent Pathogenic Microdeletions and Microduplications in Over 9500 Pregnancies.

Grati F, Gomes DM, Ferreira JCPB, Dupont C, Alesi V, Gouas L, Horelli-Kuitunen N, Choy KW, Garcia-Herrero S, Gonzalez de la Vega A, Piotrowski K, Genesio R, Queipo G, Malvestiti B, Herve B, Benzacken B, Novelli A, Vago P, Piippo K, Leung TY, Maggi F, Quibel T, Tabet AC, Simoni G, Vialard F

Prenatal Diag 2015;35(8): 801 - 809


TBX6 Null Variants and a Common Hypomorphic Allele in Congenital Scoliosis.

Wu N, Ming X, Xiao J, Wu Z, Chen X, Shinawi M, Shen Y, Yu G, Liu J, Xie H, Gucev ZS, Liu S, Yang N, AI-Kateb H, Chen J, Zhang J, Hauser N, Zhang T, Tasic V, Liu P, Su X, Pan X, Liu C, Wang L, Shen J, Chen Y, Zhang T, Zhang J, Choy KW, Wang J, Wang Q, Liu S, Zhou W, Guo J, Wang Y, Zhang C

N Engl J Med 2015;372(4): 341 - 350


Up-regulation of Cathepsin G in the Development of Chronic Postsurgical Pain.

Liu X, Tian Y, Meng Z, Chen Y, Ho IHT, Choy KW, Lichtner P, Wong SH, Yu J, Gin T, Wu WKK, Cheng CHK, Chan MTV

Anesthesiology 2015;123(4): 838 - 850


A Patient with Five Chromosomal Rearrangement and a 2q31.1 Microdeletion.

Wang T, Mao J, Liu MJ, Choy KW, Li HB, Cram DS, Li H, Chen Y

Clin Chim Acta 2014;2014(430C): 129 - 133


A Robust Approach for Blind Detection of Balanced Chromosomal Rearrangements with Whole-Genome Low-Coverage Sequencing.

Dong Z, Jiang LP, Yang CC, Hu H, Wang XH, Chen HX, Choy KW, Hu HM, Dong YL, Hu B, Xu JC, Long Y, Cao SJ, Chen H, Wang WJ, Jiang H, Xu FP, Yao H, Xu X, Liang ZQ

Hum Mutat 2014;35(5): 625 - 636


BACs-on-beads A New Robust and Rapid Detection Method For Prenatal Diagnosis.

Choy KW, Chen Y, Sun XF, Kwok YKY, Leung TY

Expert Rev Mol Diagn 2014;14(3): 273 - 280


Diagnostic Accuracy of the Bacs-on-Beads ™ Assay Versus Karyotyping for Prenatal Detection of Chromosomal Abnormalities: A Retrospective Consecutive Case Series.

Choy KW, Kwok YKY, Cheng YKY, Wong CKM, Wong HK, Leung KO , Suen AKW, Adler K, Wang CC, Lau TK, Schermer M, Lao TTH, Leung TY

BJOG 2014;121(10): 1245 - 1252


Diagnostic accuracy of the BACs-on-Beads™ assay versus karyotyping for prenatal detection of chromosomal abnormalities: a retrospective consecutive case series.

Choy K, Kwok Y, Cheng Y, Wong K, Wong H, Leung K, Suen K, Adler K, Wang C, Lau T, Schermer M, Lao T, Leung TY.

BJOG 2014; 121:1245-52.


Is High Fetal Nuchal Translucency Associated with Submicroscopic Chromosomal Abnormalities by Array CGH?

Huang J, Poon LC, Akolekar R, Choy KW, Leung TY, Nicolaides KH.

Ultrasound Obstet Gynecol 2014; 43: 620-624.


Patient's Choice between a Non-invasive Prenatal Test and Invasive Prenatal Diagnosis Based on Test Accuracy.

Chan OYM, Leung TY, Chan OK, Cheng YKY, Sahota DS

Fetal Diagn Ther 2014;35(3): 193 - 198


Performance of Chromosomal Microarray for Patients with Intellectual Disabilities/Developmental Delay, Autism, and Multiple Congenital Anomalies in a Chinese Cohort.

Chong WS, Lo FM, Lam STS, Wang CC, Luk HM, Leung TY, Choy KW

Mol Cytogenet 2014;7(34): 1 - 6


Prenatal Diagnosis of Maternally Inherited X-linked Opitz G/BBB Syndrome by Chromosomal Microarray in a Fetus with Complex Congenital Heart Disease.

Cheng YKY, Huang J, Law KM, Chan OYM, Leung TY, Choy KW

Clin Chim Acta 2014;436C(2014): 140 - 142


PSCC: Sensitive and Reliable Population-Scale Copy Number Variation Detection Method Based on Low Coverage Sequencing.

Li XC, Chen SP, Xie WW, Vogel I, Choy KW, Chen F, Christensen R, Zhang CL, Ge HJ, Jiang HJ, Yu C, Huang F, Jiang H, Zhang XQ

PLos ONE 2014;9(1): e85096


Size-based Molecular Diagnostics Using Plasma DNA for Noninvasive Prenatal Testing.

Yu JCY, Chan AKC, Zheng YWL, Jiang PY, Liao GJW, Sun H, Akolekar R, Leung TY, Go ATJI, van Vugt JMG, Minekawa R, Oudejans CBM, Nicolaides KH, Chiu RWK, Lo DYM

Proc Natl Acad Sci USA 2014;111(23): 8583 - 8588


Trends in Preterm Birth in Singleton Deliveries in a Hong Kong Population.

Hui ASY, Lao TTH, Leung TY, Schaaf JM, Sahota DS

Int J Gynecol Obstet 2014;7292(14): 248 - 253


Can Live xPlane Imaging of the In-plane View of Interventricular Septum be Used to Detect Fetal Conotruncal Anomalies?

Xiong Y, Liu T, Gan HJ, Wu Y, Xu JF, Ting YH, Leung TY, Lau TK

J Matern Fetal Neonatal Med 2013;26(4): 373 - 377


Carbimazole Embryopathy in a Chinese Population: Case Series and Literature Review.

Ting YH, Zhou Y, Lao TTH

Birth Defects Res Part A-Clin Mol Teratol 2013;97(4): 225 - 229


Detection of the Fetal Conotruncal Anomalies Using Real-time Three-dimensional Echocardiography with Live Xplane Imaging of the Fetal Ductal Arch View.

Xiong Y, Liu T, Gan HJ, Wu Y, Xu JF, Ting YH, Leung TY, Lau TK

Prenatal Diag 2013;33(5): 462 - 466


First-trimester Cystic Hygroma: Relationship of Nuchal Translucency Thickness and Outcomes.

Huang J, Leung TY, Choy KW

Obstet Gynecol 2013;121(1): 192 - 193


Melamine Toxicity in Rat Foetuses and Infants.

Wang CC, Fung KP, Fok TF, Lau TK, Pang CP, Chu KO, Shum ASW, Lam CWK, Chan MHM, Ho CS, Lau CM, Ting TL, Mak TCW

Hong Kong Med J 2013;19(S8): S20 - S22


Motivations for Undertaking DNA Sequencing-based Non-invasive Prenatal Testing for Fetal Aneuploidy: A Qualitative Study with Early Adopter Patients in Hong Kong.

Yi H, Hallowell N, Griffiths S, Leung TY

PLos ONE 2013;8(11): e81794


Noninvasive Prenatal Molecular Karyotyping from Maternal Plasma.

Yu JCY, Jiang PY, Choy KW, Chan AKC, Won HS, Leung WC, Lau ET, Tang MHY, Leung TY, Lo DYM, Chiu RWK

PLos ONE 2013;8(4): e60968


Noninvasive Twin Zygosity Assessment and Aneuploidy Detection by Maternal Plasma DNA Sequencing.

Leung TY, Qu JZZ, Liao GJW, Jiang PY, Cheng YKY, Chan AKC, Chiu RWK, Lo DYM

Prenatal Diag 2013;33(7): 675 - 681


Role of B Lymphoma Mo-MLV Insertion Region 1 in the Oncogenic Behavior of Retinoblastomas.

Ren RJ, Liu WW, Huang L, Liu DTL, Choy KW, Shi JT, Zhao JY, Zhao BW, Guan M, Shields CL, Pang CP, Li B, Yam GHF

Mol Vis 2013;19: 561 - 574


Secondary Findings from Non-invasive Prenatal Testing for Common Fetal Aneuploidies by Whole Genome Sequencing as A Clinical Service.

Lau TK, Jiang FM, Stevenson RJ, Lo TK, Chan LW, Chan MK, Lo SPS, Wang W, Zhang H, Chen F, Choy KW

Prenatal Diag 2013;33(6): 602 - 608


Single Fetal Cells for Non-Invasive Prenatal Genetic Diagnosis: Old Myths New Prospective.

Chan WK, Kwok YKY, Choy KW, Leung TY, Wang CC

Medical Journal of Obstetrics and Gynecology 2013;1(1): 1004


The Detection of Mosaicism by Prenatal BoBs TM.

Cheng YKY, Wong CKM, Wong HK, Leung Kwok On, Kwok YKY, Suen AKW, Wang CC, Leung TY, Choy KW

Prenatal Diag 2013;33(1): 42 - 49


The Influence of Image Setting on Intracranial Translucency Measurement by Manual and Semi-automated System.

Zhen L, Yang X, Ting YH, Chen M, Leung TY

Prenatal Diag 2013;33(9): 889 - 893


A Fetus with a Huge Neck Mass and a Large Abdominal Circumference - A Rare Case of Sialoblastoma and Hepatoblastoma.

Cheng YKY, Chu WCW, Law LW, Ting YH, Leung TY

Prenatal Diag 2012;32(9): 915 - 917


A Novel Way of Visualizing the Ductal and Aortic Arches by Real-time Three-dimensional Ultrasound with Live xPlane Imaging.

Xiong Y, Chen M, Chan LW, Ting YH, Fung TY, Leung TY, Lau TK

Ultrasound Obst Gyn 2012;39(3): 316 - 321


Can We Use the Frontomaxillary Facial Angle in the First Trimester to Predict Facial Cleft?

Pan M, Chen M, Sahota DS, Lao TTH, Lau TK, Leung TY

Prenatal Diag 2012;32(5): 491 - 493


Effect of Image Settings on Nuchal Translucency Thickness Measurement by a Semi-automated System.

Chen PW, Chen M, Leung TY, Lau TK

Ultrasound Obst Gyn 2012;39(2): 169 - 174


First Trimester Serum Markers Stability during Sample Transportation from the Obstetrical Site to the Screening Laboratory.

Sahota DS, Pooh RK, Choy KW, Leung TY, Lau TK

J Matern Fetal Neonatal Med 2012;25(7): 966 - 969


Has Improved Health Care Provision Impacted on the Obstetric Outcome in Teenage Women?

Lao TTH, Suen SSH, Sahota DS, Law LW, Leung TY

J Matern Fetal Neonatal Med 2012;25(8): 1358 - 1362


High Resolution Size Analysis of Fetal DNA in the Urine of Pregnant Women by Paired-end Massively Parallel Sequencing.

Tsui NBY, Jiang PY, Chow KCK, Su XX, Leung TY, Sun H, Chan AKC, Chiu RWK, Lo DYM

PLos ONE 2012;7(10): e48319


Normal Range of Intractranial Translucency (IT) Assessed by Three-dimensional Ultrasound at 11+0 to 13+6 Weeks in a Chinese Population.

Chen M, Chen H, Yang X, Wang HF, Leung TY, Sahota DS, Lao TTH, Lau TK

J Matern Fetal Neonatal Med 2012;25(5): 489 - 492


Outcome of Monochorionic Twin Pregnancies with Abnormal Umbilical Artery Doppler between 16 and 20 Weeks of Gestation.

Pan M, Chen M, Leung TY, Sahota DS, Ting YH, Lau TK

J Matern Fetal Neonatal Med 2012;25(3): 277 - 280


Quality Assurance of Nuchal Translucency for Prenatal Fetal Down Syndrome Screening.

Sahota DS, Leung WC, To WWK, Chan WP, Lau TK, Leung TY

J Matern Fetal Neonatal Med 2012;25(7): 1039 - 1043


Scan the Fetal Heart by Real-time Three-dimensional Echocardiography with Live xPlane Imaging.

Xiong Y, Chen M, Chan LW, Ting YH, Fung TY, Leung TY, Lau TK

J Matern Fetal Neonatal Med 2012;25(4): 324 - 328


Systematic Identification of Spontaneous Preterm Birth-Associated RNA Transcripts in Maternal Plasma.

Chim SSC, Lee WS, Ting YH, Chan OK, Lee SWY, Leung TY

PLos ONE 2012;7(4): e34328


Technical Concerns about Immunoprecipitation of Methylated Fetal DNA for Noninvasive Trisomy 21 Diagnosis.

Tong YK, Chiu RWK, Chan AKC, Leung TY, Lo DYM

Nat Med 2012;18(9): 1327 - 1328


2010 Report from the ISPD Special Interest Groups.

Odibo AO, Faas BHW, Oepkes D, Leung TY, Lee SM

Prenatal Diag 2011;31: 246 - 248


Assessment of Sonographer Nuchal Translucency Measurement Performance - Central Tendency and Dispersion.

Sahota DS, Chen M, Leung TY, Chan LW, Fung TY, Ting YH, Lau TK

J Matern Fetal Neonatal Med 2011;24(6): 812 - 816


Current Limitations and Difficulties in Application of Microarray Comparative Genomic Hybridization in Prenatal Diagnosis. 採用微陣列 - 比較基因組雜交進行產前診斷的局限性和困難

Chen Y, Choy KW

Chin J Med Genet 2011;28(1): 47 - 51


First Trimester Screening - New Directions for Antenatal Care?

Chitty LS, Lau TK

Prenatal Diag 2011;31(1): 1 - 2


Frontomaxillary Facial Angle at 11+0 to 13+6 Weeks in Chinese Population.

Chen M, Wang HF, Leung TY, Sahota DS, Borenstein M, Nicolaides KH, Lao TTH, Lau TK

J Matern Fetal Neonatal Med 2011;24(3): 498 - 501


Isolated Absent or Hypoplastic Nasal Bone in the Second Trimester Fetus: is Amniocentesis Necessary?

Ting YH, Lao TTH, Lau TK, Chung MK, Leung TY

J Matern Fetal Neonatal Med 2011;24(4): 555 - 558


Molecular Basis of Von Hippel-Lindau Syndrome in Chinese Patients.

Siu WK, Ma RCW, Lam CW, Mak CM, Yuen YP, Lo FMI, Chan KW, Lam SF, Ling SC, Tong SF, So WY, Chow CC, Tang MHY, Tam WH, Chan AYW

Chin Med J 2011;124(2): 237 - 241


Non-Invasive Prenatal Assessment of Trisomy 21 by Multiplexed Maternal Plasma DNA Sequencing : Large Scale Validity Study.

Chiu RWK, Akolekar R, Zheng YWL, Leung TY, Sun H, Chan AKC, Lun FMF, Go ATJI, Lau ET, To WWK, Leung WC, Tang RYK, Au Yeung KC, Lam H, Kung YY, Zhang XQ, Van Vugt JMG, Minekawa R, Tang MHY, Wang J, Oudejans CBM, Lau TK, Nicolaides KH, Lo DYM

Brit Med J 2011;342: c7401


Noninvasive Prenatal Diagnosis of Hemophilia by Microfluidics Digital PCR Analysis of Maternal Plasma DNA.

Tsui NBY, Kadir RA, Chan AKC, Chi C, Mellars G, Tuddenham EG, Leung TY, Lau TK, Chiu RWK, Lo DYM

Blood 2011;117(13): 3684 - 3691


Placental Site in The Second Trimester of Pregnancy and Its Association with Subsequent Obstetric Outcome.

Fung TY, Sahota DS, Lau TK, Leung TY, Chan LW, Chung TKH

Prenatal Diag 2011;31(6): 548 - 554


Prenatal Diagnosis of Morbidly Adherent Placenta.

Lau TK, Leung TY

Int J Obstet Anesth 2011;20(2): 107 - 109


The Use of Three-Dimensional Ultrasound Does Not Improve Training in Fetal Biometric Measurements.

Chan LW, Ting YH, Lao TTH, Chau MMC, Fung TY, Leung TY, Sahota DS, Lau TK

J Matern Fetal Neonatal Med 2011;24(9): 1173 - 1175


Use of Three-Dimensional (3D) Sonography to Assess the True Midsagittal Plane of Fetal Spine.

Yang XH, Chen M, Leung TY, Wong SM, Lau TK

J Matern Fetal Neonatal Med 2011;24(2): 297 - 300


採用微陣列 - 比較基因組雜交進行產前診斷的局限性和困難

Chen Y, Choy KW




Chen M, Hu ZY, Lau TK

Chinese Journals of Practical Medicine 2011;27(4): 105 - 108


Assessment of the Fetal Interventricular Septum Using Real-Time Three-Dimensional Echocardiography with Live 3D Imaging.

Xiong Y, Wah YMI, Chen M, Fung TY, Leung TY, Lau TK

Ultrasound Obst Gyn 2010;35(6): 754 - 755


Comparison of First-Trimester Contingent Screening Strategies for Down Syndrome.

Sahota DS, Leung TY, Chan LW, Law LW, Fung TY, Chen M, Lau TK

Ultrasound Obst Gyn 2010;35(3): 286 - 291


Comparison of Likehood Ratios of First-Trimester Nuchal Translucency Measurements: Multiples of Median, Delta or Mixture.

Sahota DS, Leung TY, Chen M, Chan LW, Fung TY, Lau TK

Ultrasound Obst Gyn 2010;36(1): 15 - 19


Learning Curve in Measurement of Fetal Frontomaxillary Facial Angle at 11-13 Weeks of Gestation.

Yang X, Chen M, Wang HF, Leung TY, Borenstein M, Nicolaides KH, Sahota DS, Lau TK

Ultrasound Obst Gyn 2010;35(5): 530 - 534


Re: Counseling in Isolated Mild Fetal Ventriculomegaly.

Chan LW, Lau TK

Ultrasound Obst Gyn 2010;35(5): 624 - 625


Real-Time Three-Dimensional Ultrasound with Live xPlane Imaging Assists First-Trimester Acquisition of a True Midsagittal Section.

Xiong Y, Wah YMI, Chan LW, Leung TY, Fung TY, Lau TK

Ultrasound Obst Gyn 2010;36(2): 136 - 140


Systematic Identification of Placental Epigenetic Signatures for the Noninvasive Prenatal Detection of Edwards Syndrome.

Tsui DWY, Lam DYM, Lee CWS, Leung TY, Lau TK, Lau ET, Tang MHY, Akolekar R, Nicolaides KH, Chiu RWK, Lo DYM, Chim SSC

PLos ONE 2010;5(11): e15069


The Impact of Human Copy Number Variation on a New Era of Genetic Testing.

Choy KW, Setlur SR, Lee C, Lau TK

BJOG 2010;117(4): 391 - 398



Lau TK, Leung TY, Chen M, Liao C

Chin J Obstet Gynecol 2010;45(6)



Lau TK, Leung TY, Chen M, Liao C

Chin J Obstet Gynecol 2010;45(10): 732 - 734


A survey of prenatal first-trimester aneuploidy screening among Hong Kong specialist obstetricians.

Chan OYM, Sahota DS, Chan OK, Leung TY, Lau TK

Hong Kong Med J 2009;15(6): 447 - 451


Assessing discrepant findings between QF-PCR on uncultured prenatal samples and karyotyping on long-term culture.

Lau ET, Tang L, Wong C, Lam YH, Ghosh A, Leung WC, Sin WK, Lau TK, Kung YY, Tang MHY

Prenatal Diag 2009;29(2): 151 - 155


Chinese women's preferences for prenatal diagnostic procedure and their willingness to trade between procedures.

Chan OYM, Sahota DS, Leung TY, Choy KW, Chan OK, Lau TK

Prenatal Diag 2009;29(13): 1270 - 1276


De novo 16p13.11 microdeletion identified by high-resolution array CGH in a fetus with increased nuchal translucency.

Law LW, Lau TK, Fung TY, Leung TY, Wang CC, Choy KW

BJOG 2009;116(2): 339 - 343


Development of extraction protocols to improve the yield for fetal RNA in maternal plasma.

Heung MS, Tsui NBY, Leung TY, Lau TK, Lo DYM, Chiu Rossa WK

Prenatal Diag 2009;29(3): 277 - 279


First trimester measurements of nasal bone length using three-dimensional ultrasound.

Chen M, Wang HF, Leung TY, Fung TY, Chan LW, Sahota DS, Lao TTH, Lau TK

Prenatal Diag 2009;29(8): 766 - 770


Gastroschisis Associated with an Intra-abdominal Umbilical Vein Varix: A Report of 2 Cases.

Fung TY, Chan LW, Leung TY, Lau TK

Fetal Diagn Ther 2009;25(4): 404 - 406


Medians and correction factors for biochemical and ultrasound markers in Chinese women undergoing first-trimester screening for trisomy 21.

Sahota DS, Leung TY, Fung TY, Chan LW, Law LW, Lau TK

Ultrasound Obst Gyn 2009;33(4): 387 - 393


Miscarriage after invasive prenatal diagnostic procedures: how much risk our pregnant women are willing to take?

Chan OYM, Sahota DS, Chan OK, Leung TY, Lau TK

Prenatal Diag 2009;29(9): 870 - 874


Monozygotic Dichorionic Twins Heterokaryotypic for Duplication Chromosome 2q13-q23.3.

Leung WC, Choi H, Lau WL, Ng LKI, Lau ET, Lo FM, Choy KW, Lau TK, Tang MHY, Chin RKH

Fetal Diagn Ther 2009;25(4): 397 - 399


Non-invasive Prenatal Diagnosis: From Dream to Reality.

Lau TK, Leung TY

JPOG 2009;35(3): 125 - 131


Placenta-derived fetal specific mRNA is more readily detectable in maternal plasma than in whole blood.

Heung MS, Jin SN, Tsui NBY, Ding CM, Leung TY, Lau TK, Chiu Rossa WK, Lo DYM

PLos ONE 2009;4(6): e5858


Prenatal findings and delineation of de novo concurrent partial trisomy 7q(7q31.2 --> qter) and partial monosomy 6q(6q26 --> qter) by high-resolution array CGH.

Choy KW, Chan LW, Tang MHY, Ng LKI, Leung TY, Lau TK

J Matern Fetal Neonatal Med 2009;22(11): 1014 - 1020


Real-time three-dimensional echocardiography using a matrix probe with live xPlane imaging of the interventricular septum.

Xiong Y, Wah YMI, Chen M, Leung TY, Lau TK

Ultrasound Obst Gyn 2009;34(5): 534 - 537


Sonographic features of anorectal atresia at 12 weeks.

Chen M, Meagher S, Simpson I, Lau TK

J Matern Fetal Neonatal Med 2009;22(10): 931 - 933


Study on the applicability of frontomaxillary facial angle in the first-trimester trisomy 21 fetuses in Chinese population.

Chen M, Yang X, Leung TY, Sahota DS, Fung TY, Chan LW, Lao TTH, Lau TK

Prenatal Diag 2009;29(12): 1141 - 1144


The Effect of Volume of Chorionic Villi on Long-Term Cell Culture.

Chen M, Ng LKI, Lau ET, Lee CP, Tang MHY, Lam YH

Fetal Diagn Ther 2009;24(4): 409 - 412


Ultrasound screening for fetal structural abnormalities performed by trained midwives in the second trimester in a low-risk population-an appraisal.

Chen M, Leung TY, Sahota DS, Fung TY, Chan LW, Law LW, Chau MMC, Lao TTH, Lau TK

Acta Obstet Gyn Scan 2009;88(6): 713 - 719


Volumetric (3D) imaging reduces inter- and intraobserver variation of fetal biometry measurements.

Chan LW, Fung TY, Leung TY, Sahota DS, Lau TK

Ultrasound Obst Gyn 2009;33(4): 447 - 452


A prospective study on the effect of rapid aneuploidy testing (amnio-PCR) on anxiety levels and quality of life measures in women and their partners with positive Down screening result.

Leung WC, Lau ET, Ngai C, Lam H, Leung KY, Lee CP, Lao TTH, Tang MHY

Fetal Diagn Ther 2008;24(3): 165 - 169


Expectation and Knowledge of Pregnant Women Undergoing First and Second Trimester Ultrasound Examination in a Chinese Population.

Chan LW, Chan OK, Chau MMC, Sahota DS, Leung TY, Fung TY, Lau TK

Prenatal Diag 2008;28(8): 739 - 744


Fetal Biometry in Ethnic Chinese: Biparietal Diameter, Head Circumference, Abdominal Circumference and Femur Length.

Leung TN, Pang MW, Sahota DS, Leung TY, Poon CF, Wong SM, Lau TK

Ultrasound Obst Gyn 2008;31(3): 321 - 327


Fetal nasal bone status in Chinese women undergoing first-trimester screening for trisomy 21.

Leung TY, Sahota DS, Chan LW, Law LW, Fung TY, Lau TK

Am J Obstet Gynecol 2008;199(5): 521.e1 - 521.e5


How true is a 'true' midsagittal section?

Wah YMI, Chan LW, Leung TY, Fung TY, Lau TK

Ultrasound Obst Gyn 2008;32(7): 855 - 859


Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma.

Chiu Rossa WK, Chan AKC, Gao Y, Lau VYM, Zheng W, Leung TY, Foo CHF, Xie B, Tsui NBY, Lun FMF, Zee BCY, Lau TK, Cantor CR, Lo DYM

Proc Natl Acad Sci USA 2008;105(51): 20458 - 20463


Noninvasive prenatal diagnosis of monogenic diseases by digital size selection and relative mutation dosage on DNA in maternal plasma.

Lun FMF, Tsui NBY, Chan AKC, Leung TY, Lau TK, Charoenkwan P, Chow KCK, Lo WYW, Wanapirak C, Sanguansermsri T, Cantor CR, Chiu Rossa WK, Lo DYM

Proc Natl Acad Sci USA 2008;105(50): 19920 - 19925


Prediction of birth weight by fetal crown-rump length and maternal serum levels of pregnancy-associated plasma protein-A in the first trimester.

Leung TY, Sahota DS, Chan LW, Law LW, Fung TY, Leung TN, Lau TK

Ultrasound Obst Gyn 2008;31(1): 10 - 14


Prenatal Screening for Retinoblastoma in Hong Kong.

Lau CSL, Choy KW, Fan DSP, Yu CBO, Wong CY, Lam DSC, Pang CCP

Hong Kong Med J 2008;14(5): 391 - 394


Screening for Trisomy 21 by Maternal Age, Fetal Nuchal Translucency Thickness, Free Beta-Human Chorionic Gonadotropin and Pregnancy-Associated Plasma Protein-A.

Kagan KO, Wright D, Baker A, Sahota DS, Nicolaides KH

Ultrasound Obst Gyn 2008;31(6): 618 - 624


Second-Trimester Sonographic Soft Markers: What Can We Learn From the Experience of First-Trimester Nuchal Translucency Screening?

Lau TK, Evans MI

Ultrasound Obst Gyn 2008;32(2): 123 - 125


Umbilical cord ulceration causing foetal haemorrhage and stillbirth.

Chan SSC, Lau APK, To KF, Leung TY, Lau TK, Leung TN

Hong Kong Med J 2008;14(2): 148 - 151


First-trimester combined screening for trisomy 21 in a predominantly Chinese population.

Leung TY, Chan LW, Leung TN, Fung TY, Sahota DS, Spencer K, Lau TK

Ultrasound Obst Gyn 2007;29(1): 14 - 17


Microphthalmos Associated with Dartmouth Combination Chemotherapy in Pregnancy.

Li HW, Tam WH, Ng PC, Mok TSK, Tam BSM, Lau TK

J Reprod Med 2007;52(6): 575 - 576


Quantitative aberrations of hypermethylated RASSF1A gene sequences in maternal plasma in pre-eclampsia.

Tsui DWY, Chan AKC, Chim SSC, Chan LW, Leung TY, Lau TK, Lo DYM, Chiu Rossa WK

Prenatal Diag 2007;27(13): 1212 - 1218


Ex utero intrapartum treatment (EXIT) for congenital giant ranula.

Chan DFY, Lee CH, Fung TY, Chan LW, Abdullah V, Ng PC

Acta Paediatr 2006;95(10): 1303 - 1305


Left ventricular diastolic function during normal pregnancy: assessment by spectral tissue Doppler imaging.

Fok AWY, Chan Louis YS, Wong JTH, Yu CM, Lau TK

Ultrasound Obst Gyn 2006;28(6): 789 - 793


Risk factors for procedure-related fetal losses after mid-trimester genetic amniocentesis.

Kong CW, Leung TN, Leung TY, Chan LW, Sahota DS, Fung TY, Lau TK

Prenatal Diag 2006;26(10): 925 - 930


Ruptured Pulmonary Arteriovenous Malformation During Pregnancy.

Wong ASW, Cheung GWY, Manlulu AV, Wan IYP, Chu MC, Yu SCH, Tam WH, Yim APC

Acta Obstet Gyn Scan 2006;85(10): 1273 - 1275


Congenital systemic Langerhans cell histiocytosis presenting as hydrops fetalis.

Lee CH, Lau TK, To KF, Lam HS, Chan AWH, Ng PC

Acta Paediatr 2005;94(12): 1843 - 1847


Detection of the placental epigenetic signature of the maspin gene in maternal plasma.

Chim SSC, Tong YK, Chiu Rossa WK, Lau TK, Leung TN, Chan LYS, Oudejans CBM, Ding CM, Lo DYM

Proc Natl Acad Sci USA 2005;102(41): 14753 - 14758


Expectation and knowledge of women undergoing first-trimester combined screening for Down syndrome in a Chinese population.

Chan LW, Chau MMC, Leung TY, Fung TY, Leung TN, Lau TK

Prenatal Diag 2005;25(13): 1248 - 1252


Fetal intra-abdominal umbilical vein varix: what is the clinical significance?

Fung TY, Leung TN, Leung TY, Lau TK

Ultrasound Obst Gyn 2005;25(2): 149 - 154


Genetic screening and diagnosis.

Lau TK, Leung TN

Curr Opin Obstet Gyn 2005;17(2): 163 - 169


Outcome of 1355 consecutive transabdominal chorionic villus samplings in 1351 patients.

Lau TK, Leung TY, Fung TY, Chan LW, Sahota DS, Leung TN

Chin Med J 2005;118(20): 1675 - 1681


Prenatal embolisation of a large chorioangioma using enbucrilate.

Lau TK, Yu SCH, Leung TY, To KF, Fung TY, Leung TN

BJOG 2005;112(7): 1002 - 1004


Reference charts of gestation-specific tissue Doppler imaging indices of systolic and diastolic functions in the normal fetal heart.

Chan Louis YS, Fok AWY, Wong JTH, Yu CM, Leung TN, Lau TK

Am Heart J 2005;150(4): 750 - 755


A validation study of ultrasonic foetal weight estimation models for Hong Kong Chinese singleton pregnancies.

Pang MW, Leung TN, Lau TK

Hong Kong Med J 2004;10(6): 384 - 388


Attitudes towards termination of pregnancy among Hong Kong Chinese women attending prenatal diagnosis counselling clinic.

Leung TN, Chau MMC, Chang JJHT, Leung TY, Fung TY, Lau TK

Prenatal Diag 2004;24(7): 546 - 551


Congenital Cervical Fibrosarcoma with Hydrops Fetalis.

Lam PM, Leung TN, Ng PC, Vlantis AC, Wong W, Lau TK

Acta Obstet Gyn Scan 2004;83(8): 773 - 776


MS analysis of single-nucleotide differences in circulating nucleic acids: Application to noninvasive prenatal diagnosis.

Ding CM, Chiu Rossa WK, Lau TK, Leung TN, Chan LC, Chan Amy YY, Charoenkwan P, Ng ISL, Law HY, Ma ESK, Xu X, Wanapirak C, Sanguansermsri T, Liao C, Tan Jin Ai MA, Chui DHK, Cantor CR, Lo DYM

Proc Natl Acad Sci USA 2004;101(29): 10762 - 10767


Treatment of twin-twin transfusion syndrome by fetoscopic laser photocoagulation.

Lau TK, Leung TY, Fung TY, Leung TN

Chin Med J 2004;117(9): 1431 - 1434


Fetus with Hydropic Change Secondary to Fetal Supraventricular Tachycardia.

Yam MC, Leung TY, Lau TK, Sung RYT

HK J Paediatr 2003;8(2): 130 - 132


Genetic alterations on chromosome 19, 20, 21, 22, and X detected by loss of heterozygosity analysis in retinoblastoma.

Huang Q, Choy KW, Cheung KF, Lam DSC, Fu WL, Pang CCP

Mol Vis 2003;9: 502 - 507


Prenatal Treatment of Chorioangioma by Microcoil Embolisation.

Lau TK, Leung TY, Yu SCH, To KF, Leung TN

BJOG 2003;110(1): 70 - 73


Prenatal exclusion of beta thalassaemia major by examination of maternal plasma.

Chiu Rossa WK, Lau TK, Leung TN, Chow KCK, Chui DHK, Lo DYM

Lancet 2002;360(9338): 998 - 1000


Second-trimester ultrasonographic assessment of the umbilical coiling index.

Qin Y, Lau TK, Rogers MS

Ultrasound Obst Gyn 2002;20(5): 458 - 463


Fetal scalp cysts: challenge in diagnosis and counseling.

Lau TK, Leung TN, Leung TY, Pang MW, Tam WH

J Ultras Med 2001;20(2): 175 - 177


Prenatal Diagnosis of Intra-abdominal Mature Testicular Teratoma.

Siu NSS, Leung TN, Leung TY, Ng SW, Yeung CK, Lau TK

J Ultras Med 2001;20(11): 1257 - 1260


Rare major maternal complications after second trimester amniocentesis: sequelae of avoiding a transplacental approach.

Lau TK, Leung TN, Leung TY, Pang MW, Tam WH

Aust NZ J Obstet Gyn 2001;41(4): 472 - 473


In Utero Treatment of Hydrops Fetalis due to Parvovirus B19 Infection: a Case Report.

Ng PS, Leung TY, Leung TN, Lau TK

HKJGOM 2000;1(1): 67 - 70


Outcome of 555 Consecutive Transabdominal Chorionic Villus Samplings in a Teaching Hospital.

Lau TK, Chau MCM, Leung TY, Pang MW, Fung TY, Leung TN

HKJGOM 2000;1(1): 21 - 27


Prenatal detection of fetal Down's syndrome from maternal plasma.

Poon LLM, Leung TN, Lau TK, Lo DYM

Lancet 2000;356(924): 1819 - 1820


Response to letter to the editor by goldwurm and biondi - "Case of congenital hypotransferrinemia suggests that tissue hypoxia during fetal development may cause hypospadias.

Fung TY

Am J Med Genet 2000;95(3): 288


Homozygous alpha-thalassemia associated with hypospadias in three survivors.

Fung TY, Lau TK, Li CK, Li CK

Am J Med Genet 1999;82(3): 225 - 227


Maternal serum screening for Down syndrome in a teaching hospital in Hong Kong.(Chinese Article)

Law LK, Lau TK, Fung TY, Rogers MS, Hjelm NM

Chin Med J 1999;112(8): 754 - 757


Rapid Clearance of Fetal DNA from Maternal Plasma.

Lo DYM, Zhang J, Leung TN, Lau TK, Chang AMZ, Hjelm NM

Am J Hum Genet 1999;64(1): 218 - 224


A study of fetal sex determination in coelomic flulid.

Lau TK, Fung TY, Wong YF, Fung HYM

Gynecol Obstet Inves 1998;45( 1): 16 - 18


In Utero Exchange Transfusion in Homozygous Alpha-Thalassaemia: A Case Report.

Fung TY, Lau TK, Tam WH, Li CK

Prenatal Diag 1998;18: 838 - 841


Maternal plasma fetal DNA as a marker for preterm labour.

Leung TN, Zhang J, Lau TK, Hjelm NM, Lo DYM

Lancet 1998;352(914): 1904 - 1905


Parvovirus B19-associated hydrops foetalis: the first confirmed case in Hong Kong.

Chan PKS, To KF, Yip SK, Tam JSL, Cheng AFB

Hong Kong Med J 1998;4(3): 321 - 323


Prenatal Diagnosis of cardiac osteoma: a case report.

Fung TY, Lau TK, Yam MC, To KF

Prenatal Diag 1998;18(11): 1209 - 1211


Quantitative analysis of fetal DNA in maternal plasma and serum: implications for noninvasive prenatal diagnosis.

Lo DYM, Tein MSC, Lau TK, Haines CJ, Leung TN, Poon PMK, Wainscoat JS, Johnson PJ, Chang AMZ, Hjelm NM

Am J Hum Genet 1998;62: 768 - 775


Racial variation in incidence of Trisomy 21: A survey of 57,742 Chinese deliveries.

Lau TK, Fung HYM, Rogers MS, Cheung KL

Am J Med Genet 1998;75(4): 386 - 388


Abdomino-amniotic shunting in isolated fetal ascites with polyhydramnios.

Fung TY, Fung HYM, Lau TK, Chang AMZ

Acta Obstet Gyn Scan 1997;76(7): 706 - 707


Crown-chin length in normal and anencephalic fetuses at 10 to 14 weeks' gestation.

Sepulveda W, Sebire NJ, Fung TY, Pipi E, Nicolaides KH

Am J Obstet Gynecol 1997;176(4): 852 - 855


Fetal bowel dilatation - Report of 3 cases with different perinatal outcomes.

Lau TK, Fung HYM, Fung TY

Aust NZ J Obstet Gyn 1997;37(3): 323 - 324


Prenatal gangrene in association with twin-twin transfusion syndrome.

Dawkins RR, Rogers MS

Am J Obstet Gynecol 1995;172(3): 1055 - 1057


Congenital listeriosis: Case reports and review of literature.

Leung TN, Cheung KL, Wong FWS

Asia Oceania J Obstet Gynaecol 1994;20(2): 173 - 177


Neural-tube defect and folic acid status in Hong Kong Chinese.

Wang VW, Chang AMZ

BJOG 1993;100: 1065


Placental bands : a variant of placenta praevia?

Stock AI, Haines CJ, Wong SP, Ghosh A

BJOG 1993;100(9): 863 - 865


Non-immune hydrops fetalis.

Li CY, Lao TTH

Asia Oceania J Obstet Gynaecol 1990;16(3): 191 - 199


The importance of early prenatal diagnosis of thanatophoric dysplasia with respect to obstetric management.

Loong EPL

Eur J Obstet Gyn R B 1987;25: 145 - 152


Racial variations in the incidence of trisomy 21.

Rogers MS

BJOG 1986;93: 597 - 599


The need for chromosome diagnosis in the third trimester of pregnancy.

Loong EPL

J Obstet Gynaecol 1986;6: 215


The use of a microcomputer in the antenatal interview - a feasibility study.

Wong FWS

HK Pract 1986;8: 1650 - 1656


Ultrasound diagnosis of recurrence of Majewski Dwarfism.

Rogers MS, Cruickshank J

J.HK.Med.Assn. 1985;37: 95 - 97