Academic Publications in Perinatal Medicine


In vitro tests to evaluate embryotoxicity and irritation of Chinese herbal medicine (Pentaherbs formulation) for atopic dermatitis

Li L, Mou X, Xie H, Zhang A, Li J, Wang R, Seid A, Tang LY, Wang L, Leung PC, Spielmann H, Wang CC, Fan X

J Ethnopharmacol. 2023 Jan 8;305:116149


Adverse maternal, fetal, and newborn outcomes among pregnant women with SARS-CoV-2 infection: an individual participant data meta-analysis

Smith ER, Oakley E, Grandner GW, Ferguson K, Farooq F, Afshar Y, Ahlberg M, Ahmadzia H, Akelo V, Aldrovandi G, Tippett Barr BA, Bevilacqua E, Brandt JS, Broutet N, Fernández Buhigas I, Carrillo J, Clifton R, Conry J, Cosmi E, Crispi F, Crovetto F, Delgado-López C, Divakar H, Driscoll AJ, Favre G, Flaherman VJ, Gale C, Gil MM, Gottlieb SL, Gratacós E, Hernandez O, Jones S, Kalafat E, Khagayi S, Knight M, Kotloff K, Lanzone A, Le Doare K, Lees C, Litman E, Lokken EM, Laurita Longo V, Madhi SA, Magee LA, Martinez-Portilla RJ, McClure EM, Metz TD, Miller ES, Money D, Moungmaithong S, Mullins E, Nachega JB, Nunes MC, Onyango D, Panchaud A, Poon LC, Raiten D, Regan L, Rukundo G, Sahota D, Sakowicz A, Sanin-Blair J, Söderling J, Stephansson O, Temmerman M, Thorson A, Tolosa JE, Townson J, Valencia-Prado M, Visentin S, Von Dadelszen P, Adams Waldorf K, Whitehead C, Yassa M, Tielsch JM

BMJ Glob Health. 2023 Jan;8(1):e009495


Incidence of neonatal sepsis after universal antenatal culture-based screening of group B streptococcus and intrapartum antibiotics: A multicentre retrospective cohort study

Chan YTV, Lau SYF, Hui SYA, Ma T, Kong CW, Kwong LT, Chan D, Lee D, Mok SL, Ma V, Lo YC, Leung KY, Leung WC

BJOG. 2023 Jan;130(1):24-31


ISUOG Practice Guidelines (updated): performance of 11–14-week ultrasound scan

International Society of Ultrasound in Obstetrics and Gynecology, Bilardo CM, Chaoui R, Hyett JA, Kagan KO, Karim JN, Papageorghiou AT, Poon LC, Salomon LJ, Syngelaki A, Nicolaides KH

Ultrasound Obstet Gynecol. 2023 Jan;61(1):127-143


Uterine artery Doppler indices throughout gestation in women with and without previous Cesarean deliveries: a prospective longitudinal case-control study

Yapan P, Tachawatcharapunya S, Surasereewong S, Thongkloung P, Pooliam J, Poon LC, Wataganara T

Sci Rep. 2022 Dec 3;12(1):20913


A prospective study comparing the inflammation-related cytokine and chemokine profile from the day of blastocyst transfer to 7 weeks of gestation between pregnancies that did or did not result in a miscarriage

Zhao Y, Man GCW, Zhang R, Wong CK, Chen X, Chung JP, Wang CC, Laird S, Zhang T, Li TC

J Reprod Immunol. 2022 Dec;154:103755


Assessment of embryo morphology following perinatal exposure to aspirin, ibuprofen and paracetamol using whole embryo culture system

Moungmaithong S, Leung BW, Sahota DS, Wang CC, Leung TY, Poon LC

J Matern Fetal Neonatal Med. 2022 Dec;35(25):8786-8793


Neonatal mortality in singleton pregnancies: a 20-year retrospective study from a tertiary perinatal unit in Hong Kong

Fung GPG, Lau SL, Hui ASY, Wong STK, Tse WT, Ng PC, Sahota DS, Lam HS, Leung TY

Hong Kong Med J. 2022 Dec;28(6):430-437


The roles of newborn anthropometrics in the association between maternal weight gain and childhood cardiovascular risks

He YY, Yuen LY, Ma RCW, Catalano PM, Tam WH

Obesity (Silver Spring). 2022 Dec;30(12):2450-2458


The view of Hong Kong parents on secondary use of dried blood spots in newborn screening program

Hui LL, Nelson EAS, Deng HB, Leung TY, Ho CH, Chong JSC, Fung GPG, Hui J, Lam HS

BMC Med Ethics. 2022 Nov 1;23(1):105


Chinese herbal medicine for induced abortion in early pregnancy (before 14 weeks’ gestation)

Zhang AL, Fan XH, Shao YF, Liu XK, Wang CC, Li L

Cochrane Database of Systematic Reviews 2022 Oct; 10: CD014609


Perinatal mortality rate in multiple pregnancies: a 20-year retrospective study from a tertiary obstetric unit in Hong Kong

Lau SL, Wong STK, Tse WT, Fung GPG, Lam HS, Sahota DS, Leung TY

Hong Kong Med J 2022 Oct;28(5):347-355


Comparing IADPSG and NICE diagnostic criteria for GDM in predicting adverse pregnancy outcomes

He Y, Ma RCW, McIntyre HD, Sacks DA, Lowe J, Catalano PM, Tam WH

Diabetes Care. 2022 Sep 1;45(9):2046-2054


SARS-CoV-2-specific antibodies and neutralization capacity in breast milk following infection vs vaccination

Leung HYH, Leung BW, Gil MM, Rolle V, Moungmaithong S, Wang CC, Poon LC

Ultrasound Obstet Gynecol. 2022 Sep;60(3):425-427


Effects of strict public health measures on seroprevalence of anti-SARS-CoV-2 antibodies during pregnancy

Leung HHY, Kwok CYT, Sahota DS, Leung MBW, Lui GCY, Ng SSS, Leung WC, Chan PKS, Poon LCY

Hong Kong Med J. 2022 Aug;28(4):294-299


Iron Deficiency Anaemia and Atonic Postpartum Haemorrhage Following Labour

Lao TT, Wong LL, Hui SYA, Sahota DS

Reprod Sci. 2022 Apr;29(4):1102-1110


Prelabor short-term variability in fetal heart rate by computerized cardiotocogram and maternal fetal Doppler indices for the prediction of labor outcomes

Lam MSN, Chaemsaithong P, Kwan AHW, Wong STK, Tse AWT, Sahota DS, Leung TY, Poon LC

J Matern Fetal Neonatal Med. 2022 Apr;35(7):1318-1327


The use of ultrasound, fibronectin and other parameters to predict the success of labour induction

Lau SL, Kwan A, Tse WT, Poon LC

Best Pract Res Clin Obstet Gynaecol. 2022 Mar;79:27-41


A prospective study comparing inflammation-related cytokine and chemokine profile from the day of blastocyst transfer to 7 weeks of gestation between miscarriage and live birth.

Zhao YW, Man GCW, Zhang RZ, Wong CK, Chen XY, Chung JPW, Wang CC, Laird S, Zhang T, Li TC.

Journal of Reproductive Immunology. 2022,103755


The impact of oral carbohydrate-rich supplement taken two hours before caesarean delivery on maternal and neonatal perioperative outcomes - a randomised clinical trial

He Y, Liu C, Han Y, Huang Y, Zhou J, Xie Q

BMC Pregnancy Childbirth. 2021 Oct 7;21(1):682


Bronchopulmonary sequestration successfully treated with prenatal radiofrequency ablation of the feeding artery

Tse WT, Poon LC, Wah YMI, Hui ASY, Ting YH, Leung TY

Ultrasound Obstet Gynecol. 2021 Aug;58(2):325-327


Association between neonatal birthweight and risk of maternal glucose intolerance after gestational diabetes mellitus

Li Z, Wang D, Cheng Y, Chen P, Ding W, Wang Z

J Diabetes Investig. 2021 Mar;12(3):425-433


Genotype-phenotype study and expansion of ARL6IP1-related complicated hereditary spastic paraplegia

Cao Y, Manning M, Pope K, He W, Vetrini F, Siskind C, Rosenfeld JA, Yang Y, Xiao R

Clin Genet. 2021 Mar;99(3):477-480


Effects of coronavirus disease 2019 (COVID-19) on maternal, perinatal and neonatal outcomes: a systematic review

Juan J, Gil MM, Rong Z, Zhang Y, Yang H, Poon LC

Ultrasound Obstet Gynecol. 2020 Jul;56(1):15-27


Reproductive,obstetric,and perinatal outcomes of women with adenomyosis and endometriosis:a systematic review and meta-analysis

Horton J, Sterrenburg M, Lane S, Maheshwari A, Li TC, Cheong Y

Hum Reprod Update. 2019 Sep 11;25(5):593-633


Analysis of fragment size distribution of cell-free DNA: A potential non-invasive marker to monitor graft damage in living-related liver transplantation for inborn errors of metabolism

Ng H, Zhu X, Xuan L, Long Y, Mao Y, Shi Y, Sun L, Liang B, Scaglia F, Choy KW, Zhu Z

Mol Genet Metab. 2019 May;127(1):45-50


Impact of the two-dose rubella vaccination regimen on incidence of rubella seronegativity in gravidae aged 25 years and younger

Hui SYA, Sahota DS, Lao TT

PLoS One. 2017 Aug 30;12(8):e0183630 (Pages 1-11)


Lhx1/5 control dendritogenesis and spine morphogenesis of Purkinje cells via regulation of Espin

Lui NC, Tam WY, Gao C, Huang JD, Wang CC, Jiang L, Yung WH, Kwan KM

Nat Commun. 2017 May 18;8:15079


Effect of Assisted Reproductive Technology on Fetal Brain Development Assessed by Prenatal Ultrasonography.

Yin L, Xu Y, Li H, Ling C, Choy KW, Xia F, Deng X

J Perinat Med 2015;43(1): 103 - 109


Prenatal Diagnosis of 24 Cases of Microduplication 22q11.2: An Investigation of Phenotype-genotype Correlations.

Dupont C, Grati F, Choy KW, Jaillard S, Toutain J, Maurin ML, Martinez-Conejero JA, Beneteau C, Coussement A, Molinagomes D, Horelli-Kuitunen N, Aboura A, Tabet AC, Besseau-Ayasse J, Bessieres GB, Simoni G, Ayala G, Benzacken B, Vialard F

Prenatal Diag 2015;35(1): 35 - 43


Prevalence of Recurrent Pathogenic Microdeletions and Microduplications in Over 9500 Pregnancies.

Grati F, Gomes DM, Ferreira JCPB, Dupont C, Alesi V, Gouas L, Horelli-Kuitunen N, Choy KW, Garcia-Herrero S, Gonzalez de la Vega A, Piotrowski K, Genesio R, Queipo G, Malvestiti B, Herve B, Benzacken B, Novelli A, Vago P, Piippo K, Leung TY, Maggi F, Quibel T, Tabet AC, Simoni G, Vialard F

Prenatal Diag 2015;35(8): 801 - 809


TBX6 Null Variants and a Common Hypomorphic Allele in Congenital Scoliosis.

Wu N, Ming X, Xiao J, Wu Z, Chen X, Shinawi M, Shen Y, Yu G, Liu J, Xie H, Gucev ZS, Liu S, Yang N, AI-Kateb H, Chen J, Zhang J, Hauser N, Zhang T, Tasic V, Liu P, Su X, Pan X, Liu C, Wang L, Shen J, Chen Y, Zhang T, Zhang J, Choy KW, Wang J, Wang Q, Liu S, Zhou W, Guo J, Wang Y, Zhang C

N Engl J Med 2015;372(4): 341 - 350


Accurate Description of DNA-based Noninvasive Prenatal Screening.

Cheung SW, Petal A, Leung TY

N Engl J Med 2015;372(17): 1675 - 1677


Ethical Concerns in the Implementation of DNA Sequencing-based Noninvasive Prenatal Testing for Fetal Aneuploidy Among Obstetric Professionals in Hong Kong.

Yi H, NganOMY, Griffiths S, Sahota DS

Am. J Bioeth 2015;6(1): 81 - 93


Noninvasive Prenatal Testing by Nanopore Sequencing of Maternal Plasma DNA: Feasibility Assessment.

Cheng SH, Jiang PY, Sun K, Cheng YKY, Chan AKC, Leung TY, Chiu RWK, Lo DYM

Clin Chem 2015;61(10): 1305 - 1306


Noninvasive Testing for Fetal Aneuploidy: A Hong Kong Perspective.

Sahota DS

Am. J Bioeth 2015;6(1): 106 - 110


Plasma DNA Tissue Mapping by Genome-Wide Methylation Sequencing for Noninvasive Prenatal, Cancer, and Transplantation Assessments.

Sun K, Jiang PY, Chan AKC, Wong J, Cheng YKY, Liang RHS, Chan WK, Ma ESK, Chan SL, Cheng SH, Chan RWY, Tong YK, Ng SSM, Wong RSM, Hui DSC, Leung TN, Leung TY, Lai PBS, Chiu RWK, Lo DYM

Proc Natl Acad Sci USA 2015;112(40): e5503 - e5512


Umbilical and fetal middle cerebral artery Doppler at 30-34 weeks' gestation in the prediction of adverse perinatal outcome.

Bakalis S, Akolekar R, Gallo DM,ƒ Poonƒ LC*,ƒ Nicolaidesƒ KH.

Ultrasound Obstet Gynecol 2015; 45: 409-420.


Umbilical and fetal middle cerebral artery Doppler at 35-37 weeks' gestation in the prediction of adverse perinatal outcome.

Akolekar R, Syngelaki A, Gallo DM,ƒ Poonƒ LC,ƒ Nicolaidesƒ KH.

Ultrasound Obstet Gynecol 2015; 46: 82-92.


Women's Uptake of Non-Invasive DNA Testing Following a High-risk Screening Test for Trisomy 21 within a Publicly Funded Healthcare System Findings from a Retrospective Review.

Chan OYM, Leung WC, Chan WP, Leung TY, Cheng YKY, Sahota DS

Prenatal Diag 2015;35(4): 342 - 347


A Patient with Five Chromosomal Rearrangement and a 2q31.1 Microdeletion.

Wang T, Mao J, Liu MJ, Choy KW, Li HB, Cram DS, Li H, Chen Y

Clin Chim Acta 2014;2014(430C): 129 - 133


A Robust Approach for Blind Detection of Balanced Chromosomal Rearrangements with Whole-Genome Low-Coverage Sequencing.

Dong Z, Jiang LP, Yang CC, Hu H, Wang XH, Chen HX, Choy KW, Hu HM, Dong YL, Hu B, Xu JC, Long Y, Cao SJ, Chen H, Wang WJ, Jiang H, Xu FP, Yao H, Xu X, Liang ZQ

Hum Mutat 2014;35(5): 625 - 636


BACs-on-beads A New Robust and Rapid Detection Method For Prenatal Diagnosis.

Choy KW, Chen Y, Sun XF, Kwok YKY, Leung TY

Expert Rev Mol Diagn 2014;14(3): 273 - 280


Diagnostic accuracy of the BACs-on-Beads™ assay versus karyotyping for prenatal detection of chromosomal abnormalities: a retrospective consecutive case series.

Choy K, Kwok Y, Cheng Y, Wong K, Wong H, Leung K, Suen K, Adler K, Wang C, Lau T, Schermer M, Lao T, Leung TY.

BJOG 2014; 121:1245-52.


Is High Fetal Nuchal Translucency Associated with Submicroscopic Chromosomal Abnormalities by Array CGH?

Huang J, Poon LC, Akolekar R, Choy KW, Leung TY, Nicolaides KH.

Ultrasound Obstet Gynecol 2014; 43: 620-624.


Performance of Chromosomal Microarray for Patients with Intellectual Disabilities/Developmental Delay, Autism, and Multiple Congenital Anomalies in a Chinese Cohort.

Chong WS, Lo FM, Lam STS, Wang CC, Luk HM, Leung TY, Choy KW

Mol Cytogenet 2014;7(34): 1 - 6


Prenatal Diagnosis of Maternally Inherited X-linked Opitz G/BBB Syndrome by Chromosomal Microarray in a Fetus with Complex Congenital Heart Disease.

Cheng YKY, Huang J, Law KM, Chan OYM, Leung TY, Choy KW

Clin Chim Acta 2014;436C(2014): 140 - 142


PSCC: Sensitive and Reliable Population-Scale Copy Number Variation Detection Method Based on Low Coverage Sequencing.

Li XC, Chen SP, Xie WW, Vogel I, Choy KW, Chen F, Christensen R, Zhang CL, Ge HJ, Jiang HJ, Yu C, Huang F, Jiang H, Zhang XQ

PLos ONE 2014;9(1): e85096


Trends in Preterm Birth in Singleton Deliveries in a Hong Kong Population.

Hui ASY, Lao TTH, Leung TY, Schaaf JM, Sahota DS

Int J Gynecol Obstet 2014;7292(14): 248 - 253


Patient's Choice between a Non-invasive Prenatal Test and Invasive Prenatal Diagnosis Based on Test Accuracy.

Chan OYM, Leung TY, Chan OK, Cheng YKY, Sahota DS

Fetal Diagn Ther 2014;35(3): 193 - 198


Size-based Molecular Diagnostics Using Plasma DNA for Noninvasive Prenatal Testing.

Yu JCY, Chan AKC, Zheng YWL, Jiang PY, Liao GJW, Sun H, Akolekar R, Leung TY, Go ATJI, van Vugt JMG, Minekawa R, Oudejans CBM, Nicolaides KH, Chiu RWK, Lo DYM

Proc Natl Acad Sci USA 2014;111(23): 8583 - 8588


Can Live xPlane Imaging of the In-plane View of Interventricular Septum be Used to Detect Fetal Conotruncal Anomalies?

Xiong Y, Liu T, Gan HJ, Wu Y, Xu JF, Ting YH, Leung TY, Lau TK

J Matern Fetal Neonatal Med 2013;26(4): 373 - 377


Carbimazole Embryopathy in a Chinese Population: Case Series and Literature Review.

Ting YH, Zhou Y, Lao TTH

Birth Defects Res Part A-Clin Mol Teratol 2013;97(4): 225 - 229


Detection of the Fetal Conotruncal Anomalies Using Real-time Three-dimensional Echocardiography with Live Xplane Imaging of the Fetal Ductal Arch View.

Xiong Y, Liu T, Gan HJ, Wu Y, Xu JF, Ting YH, Leung TY, Lau TK

Prenatal Diag 2013;33(5): 462 - 466


First-trimester Cystic Hygroma: Relationship of Nuchal Translucency Thickness and Outcomes.

Huang J, Leung TY, Choy KW

Obstet Gynecol 2013;121(1): 192 - 193


Melamine Toxicity in Rat Foetuses and Infants.

Wang CC, Fung KP, Fok TF, Lau TK, Pang CP, Chu KO, Shum ASW, Lam CWK, Chan MHM, Ho CS, Lau CM, Ting TL, Mak TCW

Hong Kong Med J 2013;19(S8): S20 - S22


Motivations for Undertaking DNA Sequencing-based Non-invasive Prenatal Testing for Fetal Aneuploidy: A Qualitative Study with Early Adopter Patients in Hong Kong.

Yi H, Hallowell N, Griffiths S, Leung TY

PLos ONE 2013;8(11): e81794


Noninvasive Prenatal Molecular Karyotyping from Maternal Plasma.

Yu JCY, Jiang PY, Choy KW, Chan AKC, Won HS, Leung WC, Lau ET, Tang MHY, Leung TY, Lo DYM, Chiu RWK

PLos ONE 2013;8(4): e60968


Noninvasive Twin Zygosity Assessment and Aneuploidy Detection by Maternal Plasma DNA Sequencing.

Leung TY, Qu JZZ, Liao GJW, Jiang PY, Cheng YKY, Chan AKC, Chiu RWK, Lo DYM

Prenatal Diag 2013;33(7): 675 - 681


Radiofrequency Ablation for Selective Reduction in Complicated Monochorionic Multiple Pregnancies.

Lu J, Ting YH, Law KM, Lau TK, Leung TY

Fetal Diagn Ther 2013;34(4): 211 - 216


Role of B Lymphoma Mo-MLV Insertion Region 1 in the Oncogenic Behavior of Retinoblastomas.

Ren RJ, Liu WW, Huang L, Liu DTL, Choy KW, Shi JT, Zhao JY, Zhao BW, Guan M, Shields CL, Pang CP, Li B, Yam GHF

Mol Vis 2013;19: 561 - 574


Secondary Findings from Non-invasive Prenatal Testing for Common Fetal Aneuploidies by Whole Genome Sequencing as A Clinical Service.

Lau TK, Jiang FM, Stevenson RJ, Lo TK, Chan LW, Chan MK, Lo SPS, Wang W, Zhang H, Chen F, Choy KW

Prenatal Diag 2013;33(6): 602 - 608


Single Fetal Cells for Non-Invasive Prenatal Genetic Diagnosis: Old Myths New Prospective.

Chan WK, Kwok YKY, Choy KW, Leung TY, Wang CC

Medical Journal of Obstetrics and Gynecology 2013;1(1): 1004


The Detection of Mosaicism by Prenatal BoBs TM.

Cheng YKY, Wong CKM, Wong HK, Leung Kwok On, Kwok YKY, Suen AKW, Wang CC, Leung TY, Choy KW

Prenatal Diag 2013;33(1): 42 - 49


The Influence of Image Setting on Intracranial Translucency Measurement by Manual and Semi-automated System.

Zhen L, Yang X, Ting YH, Chen M, Leung TY

Prenatal Diag 2013;33(9): 889 - 893


A Fetus with a Huge Neck Mass and a Large Abdominal Circumference - A Rare Case of Sialoblastoma and Hepatoblastoma.

Cheng YKY, Chu WCW, Law LW, Ting YH, Leung TY

Prenatal Diag 2012;32(9): 915 - 917


A Novel Way of Visualizing the Ductal and Aortic Arches by Real-time Three-dimensional Ultrasound with Live xPlane Imaging.

Xiong Y, Chen M, Chan LW, Ting YH, Fung TY, Leung TY, Lau TK

Ultrasound Obst Gyn 2012;39(3): 316 - 321


Can We Use the Frontomaxillary Facial Angle in the First Trimester to Predict Facial Cleft?

Pan M, Chen M, Sahota DS, Lao TTH, Lau TK, Leung TY

Prenatal Diag 2012;32(5): 491 - 493


First Trimester Serum Markers Stability during Sample Transportation from the Obstetrical Site to the Screening Laboratory.

Sahota DS, Pooh RK, Choy KW, Leung TY, Lau TK

J Matern Fetal Neonatal Med 2012;25(7): 966 - 969


Has Improved Health Care Provision Impacted on the Obstetric Outcome in Teenage Women?

Lao TTH, Suen SSH, Sahota DS, Law LW, Leung TY

J Matern Fetal Neonatal Med 2012;25(8): 1358 - 1362


High Resolution Size Analysis of Fetal DNA in the Urine of Pregnant Women by Paired-end Massively Parallel Sequencing.

Tsui NBY, Jiang PY, Chow KCK, Su XX, Leung TY, Sun H, Chan AKC, Chiu RWK, Lo DYM

PLos ONE 2012;7(10): e48319


Normal Range of Intractranial Translucency (IT) Assessed by Three-dimensional Ultrasound at 11+0 to 13+6 Weeks in a Chinese Population.

Chen M, Chen H, Yang X, Wang HF, Leung TY, Sahota DS, Lao TTH, Lau TK

J Matern Fetal Neonatal Med 2012;25(5): 489 - 492


Scan the Fetal Heart by Real-time Three-dimensional Echocardiography with Live xPlane Imaging.

Xiong Y, Chen M, Chan LW, Ting YH, Fung TY, Leung TY, Lau TK

J Matern Fetal Neonatal Med 2012;25(4): 324 - 328


Systematic Identification of Spontaneous Preterm Birth-Associated RNA Transcripts in Maternal Plasma.

Chim SSC, Lee WS, Ting YH, Chan OK, Lee SWY, Leung TY

PLos ONE 2012;7(4): e34328


Technical Concerns about Immunoprecipitation of Methylated Fetal DNA for Noninvasive Trisomy 21 Diagnosis.

Tong YK, Chiu RWK, Chan AKC, Leung TY, Lo DYM

Nat Med 2012;18(9): 1327 - 1328


Quality Assurance of Nuchal Translucency for Prenatal Fetal Down Syndrome Screening.

Sahota DS, Leung WC, To WWK, Chan WP, Lau TK, Leung TY

J Matern Fetal Neonatal Med 2012;25(7): 1039 - 1043


Assessment of Sonographer Nuchal Translucency Measurement Performance - Central Tendency and Dispersion.

Sahota DS, Chen M, Leung TY, Chan LW, Fung TY, Ting YH, Lau TK

J Matern Fetal Neonatal Med 2011;24(6): 812 - 816


Comparison of Perinatal Outcomes of Shoulder Dystocia Alleviated by Different Type and Sequence of Manoeuvres: a Retrospective Review.

Leung TY, Stuart O, Suen SSH, Sahota DS, Lau TK, Lao TTH

BJOG 2011;118(8): 985 - 990


First Trimester Screening - New Directions for Antenatal Care?

Chitty LS, Lau TK

Prenatal Diag 2011;31(1): 1 - 2


Frontomaxillary Facial Angle at 11+0 to 13+6 Weeks in Chinese Population.

Chen M, Wang HF, Leung TY, Sahota DS, Borenstein M, Nicolaides KH, Lao TTH, Lau TK

J Matern Fetal Neonatal Med 2011;24(3): 498 - 501


Isolated Absent or Hypoplastic Nasal Bone in the Second Trimester Fetus: is Amniocentesis Necessary?

Ting YH, Lao TTH, Lau TK, Chung MK, Leung TY

J Matern Fetal Neonatal Med 2011;24(4): 555 - 558


Molecular Basis of Von Hippel-Lindau Syndrome in Chinese Patients.

Siu WK, Ma RCW, Lam CW, Mak CM, Yuen YP, Lo FMI, Chan KW, Lam SF, Ling SC, Tong SF, So WY, Chow CC, Tang MHY, Tam WH, Chan AYW

Chin Med J 2011;124(2): 237 - 241


Non-Invasive Prenatal Assessment of Trisomy 21 by Multiplexed Maternal Plasma DNA Sequencing : Large Scale Validity Study.

Chiu RWK, Akolekar R, Zheng YWL, Leung TY, Sun H, Chan AKC, Lun FMF, Go ATJI, Lau ET, To WWK, Leung WC, Tang RYK, Au Yeung KC, Lam H, Kung YY, Zhang XQ, Van Vugt JMG, Minekawa R, Tang MHY, Wang J, Oudejans CBM, Lau TK, Nicolaides KH, Lo DYM

Brit Med J 2011;342: c7401


Noninvasive Prenatal Diagnosis of Hemophilia by Microfluidics Digital PCR Analysis of Maternal Plasma DNA.

Tsui NBY, Kadir RA, Chan AKC, Chi C, Mellars G, Tuddenham EG, Leung TY, Lau TK, Chiu RWK, Lo DYM

Blood 2011;117(13): 3684 - 3691


Placental Site in The Second Trimester of Pregnancy and Its Association with Subsequent Obstetric Outcome.

Fung TY, Sahota DS, Lau TK, Leung TY, Chan LW, Chung TKH

Prenatal Diag 2011;31(6): 548 - 554


Prenatal Diagnosis of Morbidly Adherent Placenta.

Lau TK, Leung TY

Int J Obstet Anesth 2011;20(2): 107 - 109


2010 Report from the ISPD Special Interest Groups.

Odibo AO, Faas BHW, Oepkes D, Leung TY, Lee SM

Prenatal Diag 2011;31: 246 - 248


Human Normal Tear Proteome.

Chu NCY, Poon TCW, Pong JCF, Pang CCP, Wang CC

Graefes Arch Clin Exp Ophthalmol 2009;247(6): 725 - 727


Is the policy of restrictive episiotomy generalisable? A prospective observational study.

Lai CY, Cheung HW, Lao TTH, Lau TK, Leung TY

J Matern Fetal Neonatal Med 2009;22(12): 1116 - 1121


Management of hypotension in obstetric spinal anaesthesia

Lee SW, Khaw KS, Ngan Kee WD, Leung TY.

Br J Anaesth. 2009;103(3):457-8


Miscarriage after invasive prenatal diagnostic procedures: how much risk our pregnant women are willing to take?

Chan OYM, Sahota DS, Chan OK, Leung TY, Lau TK

Prenatal Diag 2009;29(9): 870 - 874


Prelabor rupture of membranes at term requiring labor induction - a feature of occult fetal cephalopelvic disproportion?

Chan BCP, Leung WC, Lao TTH

J Perinat Med 2009;37(2): 118 - 123


Severe Chronic Morbidity following Childbirth.

Leung TY, Chung TKH

Best Pract Res Clin Obstet Gynaecol 2009;23(3): 401 - 423


Sociodemographic factors and pregnancy events associated with women who declined vaginal birth after cesarean section.

Pang MW, Law LW, Leung TY, Lai BPY, Lau TK

Eur J Obstet Gyn R B 2009;143(1): 24 - 28


Specific expression of Gsta4 in mouse cochlear melanocytes: a novel role for hearing and melanocyte differentiation.

Uehara S, Izumi Y, Kubo Y, Wang CC, Mineta K, Ikeo K, Gojobori T, Tachibana M, Kikuchi T, Kobayashi T, Shibahara S, Taya C, Yonekawa H, Shiroishi T, Yamamoto H

Pigment Cell Melanoma Res 2009;22(1): 111 - 119


Supplementary oxygen for emergency Caesarean section under regional anaesthesia.

Khaw KS, Wang CC, Ngan Kee WD, Tam WH, Ng F, Critchley LAH, Rogers MS

Brit J Anaesth 2009;102(1): 90 - 96


The impact of maternal height on intrapartum operative delivery: A reappraisal.

Chan BCP, Lao TTH

J Obstet Gynaecol Res 2009;35(2): 307 - 314


Comparison of Nuchal and Detailed Morphology Ultrasound Examinations in Early Pregnancy for Fetal Structural Abnormality Screening: A Randomized Controlled Trial.

Chen M, Lee CP, Lam YH, Tang RYK, Chan BCP, Wong SF, Tse LHY, Tang MHY

Ultrasound Obst Gyn 2008;31(2): 136 - 146


Fetal Biometry in Ethnic Chinese: Biparietal Diameter, Head Circumference, Abdominal Circumference and Femur Length.

Leung TN, Pang MW, Sahota DS, Leung TY, Poon CF, Wong SM, Lau TK

Ultrasound Obst Gyn 2008;31(3): 321 - 327


Fetal nasal bone status in Chinese women undergoing first-trimester screening for trisomy 21.

Leung TY, Sahota DS, Chan LW, Law LW, Fung TY, Lau TK

Am J Obstet Gynecol 2008;199(5): 521.e1 - 521.e5


Glucose intolerance and cardiometabolic risk in children exposed to maternal gestational diabetes mellitus in utero.

Tam WH, Ma RCW, Yang XL, Ko GTC, Tong PCY, Cockram CS, Sahota DS, Rogers MS, Chan JCN

Pediatrics 2008;122(6): 1229 - 1234


A prospective study on the effect of rapid aneuploidy testing (amnio-PCR) on anxiety levels and quality of life measures in women and their partners with positive Down screening result.

Leung WC, Lau ET, Ngai C, Lam H, Leung KY, Lee CP, Lao TTH, Tang MHY

Fetal Diagn Ther 2008;24(3): 165 - 169


A qualitative study of the experiences of Hong Kong Chinese women diagnosed with postnatal depression.

Chan SWC, Levy VA, Chung TKH, Lee DTS

Hong Kong Med J 2007;13(1): 24 - 27


Patients with malignant or pre-malignant cervical lesion have increased risk of becoming hepatitis B carrier.

Siu NSS, Cheung TH, Chan PKS, Lin CK, Lo KWK

J Exp Clin Cancer Res 2007;26(1): 77 - 81


Prevalence and Implications of Isolated Microscopic Hematuria in Asymptomatic Chinese Pregnant Women.

Szeto CC, To KF, Lai FM, Chow KM, Tam WH, Chung KY, Leung CB, Lui SF, Li PKT, Lau TK

Nephron Clin Pract 2007;105(4): c147 - c152


Profile of Viral Load, Integration, and E2 Gene Disruption of HPV58 in Normal Cervix and Cervical Neoplasia.

Chan PKS, Cheung JLK, Cheung TH, Lo KWK, Yim SF, Siu NSS, Tang JWT

J Infect Dis 2007;196(6): 868 - 875


Multipopulation analysis of polymorphisms in five mononucleotide repeats used to determine the microsatellite instability status of human tumors.

Buhard O, Cattaneo F, Wong YF, Yim SF, Friedman E, Flejou JF, Duval A, Hamelin R

J Clin Oncol 2006;24(2): 241 - 251


Determinants of postpartum depression symptomatology: A prospective multivariate study among Chinese women.

Lee DTS, Yip SK, Chan SSM, Lee FY, Leung TYS, Chung TKH

¤¤°ê¤ß²z½¥ÍÂø»x 2005;19(9): 626 - 631


Expectation and knowledge of women undergoing first-trimester combined screening for Down syndrome in a Chinese population.

Chan LW, Chau MMC, Leung TY, Fung TY, Leung TN, Lau TK

Prenatal Diag 2005;25(13): 1248 - 1252


Screening Test Model Using Duration of Labor for the Detection of Postpartum Urinary Retention.

Yip SK, Sahota DS, Pang MW, Chang AMZ

Neurourol Urodynam 2005;24(3): 248 - 253


Fetal intra-abdominal umbilical vein varix: what is the clinical significance?

Fung TY, Leung TN, Leung TY, Lau TK

Ultrasound Obst Gyn 2005;25(2): 149 - 154


Ethnoepidemiology of postnatal depression: Prospective multivariate study of sociocultural risk factors in a Chinese population in Hong Kong.

Lee DTS, Yip SK, Leung TYS, Chung TKH

Brit J Psychiat 2004;184(1): 34 - 40


Pregnancy and perinatal outcomes of women with severe acute respiratory syndrome.

Wong SF, Chow KM, Leung TN, Ng WF, Ng TK, Shek CC, Ng PC, Lam PWY, Ho LC, To WWK, Lai ST, Yan WW, Tan PYH

Am J Obstet Gynecol 2004;191(1): 292 - 297


A randomised controlled trial of educational counselling on the management of women who have suffered suboptimal outcomes in pregnancy.

Tam WH, Lee DTS, Chiu HFK, Ma KC, Lee A, Chung TKH

BJOG 2003;110(9): 853 - 859


Pitfalls in diagnosis of interstitial pregnancy.

Chan Louis YS, Fok AWY, Yuen PM

Acta Obstet Gyn Scan 2003;82(9): 867 - 870


Successful treatment of recurrent, intractable hyperemesis gravidarum with methylprednisolone. A case report.

Chan Louis YS, Lam MH, Lau TK, Chin RKH

J Reprod Med 2003;48(4): 293 - 295


Diabetic family history is an isolated risk factor for gestational diabetes after 30 years of age.

Chan Louis YS, Wong SF, Ho LC

Acta Obstet Gyn Scan 2002;81(2): 115 - 117


Gestational hyperlipidaemic pancreatitis.

Choy CMY, Tam WH, Leung TN

BJOG 2002;109(7): 847 - 848


Antepartum Depressive Symptomatology is Associated with Adverse Obstetric and Neonatal Outcomes.

Chung TKH, Lau TK, Yip SK, Chiu HFK, Lee DTS

Psychosom Med 2001;63(5): 830 - 834


Guidelines for HIV Testing in Pregnancy.

Fok N, Law CL, Li CY, Ngai C, Tse LHY, Tse KT

HKCOG Guidelines 2001;6: 1 - 4


High Carriage Rate of TT Virus in the Cervices of Pregnant Women.

Chan PKS, Tam WH, Yeo W, Cheung JLK, Zhong S, Cheng AFB

Clin Infect Dis 2001;32(9): 1376 - 1377


Incomplete miscarriage: a randomized controlled trial comparing oral with vaginal misoprostol for medical evacuation.

Pang MW, Lee DTS, Chung TKH

Hum Reprod 2001;16(11): 2283 - 2287


Increased placental apoptosis in pregnancies complicated by preeclampsia.

Leung TN, Smith SC, To KF, Sahota DS, Baker PN

Am J Obstet Gynecol 2001;184(6): 1249 - 1250


Influences of perinatal factors on cord blood thyroid-stimulating hormone level.

Chan Louis YS, Leung TN, Lau TK

Acta Obstet Gyn Scan 2001;80(11): 1014 - 1018


Microsatellite instability in cervical carcinoma.

Chung TKH, IP TY, Hampton GM, Wang VW, Cheung TH, Wong YF

Eur J Obstet Gyn R B 2001;94(1): 121 - 124


Oxidative stress in the fetal lamb brain following intermittent umbilical cord occlusion: a path analysis.

Rogers MS, Murray HGS, Wang CC, Pennell CE, Turner A, Ping Y, Pang CCP, Chang AMZ

BJOG 2001;108(12): 1283 - 1290


Rate of rise in maternal plasma corticotrophin-releasing hormone and its relation to gestational length.

Leung TN, Chung TKH, Madsen G, Lam PKW, Sahota DS, Smith R

BJOG 2001;108(5): 527 - 532


Relationship between birthweight and repeated courses of antenatal corticosteroids.

Lam PM, Yuen PM, Lau TK, Leung TN

Aust NZ J Obstet Gyn 2001;41(3): 281 - 284


Risk and Prediction of Preterm Delivery in Pregnancies Complicated by Antepartum Hemorrhage of Unknown Origin before 34 Weeks.

Leung TY, Chan LW, Tam WH, Leung TN, Lau TK

Gynecol Obstet Inves 2001;52(4): 227 - 231


Skull fracture and contralateral cerebral infarction after ventouse extraction.

Choy CMY, Tam WH, Ng PC

BJOG 2001;108(12): 1298 - 1299


A survey of pregnant women's attitude towards breech delivery and external cephalic version.

Leung TY, Lau TK, Lo KWK, Rogers MS

Aust NZ J Obstet Gyn 2000;40(3): 253 - 259


Cardiotocography only versus cardiotocography plus PR-interval analysis in intrapartum surveillance.

Strachan BK, Wijngaarden WJVan, Sahota DS, Chang AMZ, James DK

Lancet 2000;355(920): 456 - 459


Cell-free deoxyribonucleic acid in matrnal circulation as a marker of fetal-maternal heorrhage in patients undergoing external cephalic version near term.

Lau TK, Lo KWK, Chan LYS, Leung TY, Lo DYM

Am J Obstet Gynecol 2000;183(3): 712 - 716


Color ultrasonography: a useful technique in the identification of nuchal cord during labor.

Qin Y, Wang CC, Lau TK, Rogers MS

Ultrasound Obst Gyn 2000;15(5): 413 - 417


Determinants of umbilical cord arterial 8-iso-prostaglandin F2alpha concentrations.

Qin Y, Wang CC, Kuehn H, Rathmann J, Pang CP, Rogers MS

BJOG 2000;107(8): 973 - 981


Development of a customised birthweight standard for ethnic Chinese subjects.

Pang MW, Leung TN, Sahota DS, Lau TK, Chang AMZ

Aust NZ J Obstet Gyn 2000;40(2): 161 - 164


Effect of external cephalic version at term on fetal circulation.

Lau TK, Leung TY, Lo KWK, Fok AWY, Rogers MS

Am J Obstet Gynecol 2000;182(5): 1239 - 1242


Improving intrapartum surveillance: an individualized T/QRS ratio?

Wijngaarden WJVan, Strachan BK, Sahota DS, James DK

Eur J Obstet Gyn R B 2000;88(1): 43 - 48


Outcome of labour after successful external cephalic version at term complicated by isolated transient fetal bradycardia.

Lau TK, Lo KWK, Leung TY, Fok AWY, Rogers MS

BJOG 2000;107(3): 401 - 405


The fetal electrocardiogram: Relationship with acidemia at delivery.

Strachan BK, Sahota DS, Wijngaarden WJVan, James DK, Chang AMZ

Am J Obstet Gynecol 2000;182(3): 603 - 606


A Comparison of fetal Behaviour in breech and cephalic presentations at term.

Kean LH, Suwanrath C, Gargari SS, Sahota DS, James DK

BJOG 1999;106(11): 1209 - 1213


Dichotomization of Continuous Measurements using Generalized Additive Modelling - Application in Predicting Intrapartum Caesarean Delivery.

Hin LY, Lau TK, Rogers MS, Chang AMZ

Stat Med 1999;18(9): 1101 - 1110


Homozygous alpha-thalassemia associated with hypospadias in three survivors.

Fung TY, Lau TK, Li CK, Li CK

Am J Med Genet 1999;82(3): 225 - 227


A predictive model for the onset of spontaneous labor.

Brieger GM, Hin LY, Haines CJ, Sahota DS, Chang AMZ

Acta Obstet Gyn Scan 1998;77(1): 122 - 123


Cervical assessment by magnetic resonance imaging - its relationship to gestational age and interval to delivery.

Chan YL, Lam WWM, Lau TK, Wong SP, Li CY, Metreweli C

Brit J Radiol 1998;71(842): 155 - 159


Effect of the Duration of Labour on Postpartum Postvoid Residual Bladder Volume.

Yip SK, Hin LY, Chung TKH

Gynecol Obstet Inves 1998;45(3): 177 - 180


Emergency cervical cerclage. A study between duration of cerclage in situ with gestation at cerclage, herniation of forewater and cervical dilatation at presentation.

Yip SK, Fung HYM, Fung TY

Eur J Obstet Gyn R B 1998;78(1): 63 - 67


Lipid peroxidation in cord blood at birth: the effect of labour.

Rogers MS, Mongelli JM, Tsang BKH, Wang CC, Law KP

BJOG 1998;105( 7): 739 - 744


Computerised estimation of the baseline fetal heart rate in labour: the low frequency line.

Mongelli JM, Dawkins RR, Chung TKH, Sahota DS, Spencer JAD, Chang AMZ

BJOG 1997;104(10): 1128 - 1133


Lipid peroxidation in cord blood: a footprint of free oxygen radical activity.(Suppl)

Rogers MS, Wang VW, Wang CC, Chang AMZ

Acta Obstet Gyn Scan 1997;167(1): 20


Lipid peroxidation in cord blood: the effects of umbilical nuchal cord.

Wang CC, Rogers MS

BJOG 1997;104(2): 251 - 255


Oxygen free radical activity in the second stage of labor.

Mongelli JM, Wang CC, Wang VW, Pang CP, Rogers MS

Acta Obstet Gyn Scan 1997;76(8): 765 - 768


Prediction and prevention of perinatal morbidity in Hong Kong. (Chinese Article)

Rogers MS, Wong YF

Chin J Obstet Gynecol 1997;32: 393 - 395


The incidence of perinatal mortality associated with hyperglycaemia in pregnancy.

Roach VJ, Rogers MS

Aust NZ J Obstet Gyn 1997;37: 250 - 251


Lipid peroxide in cord blood: the effect of amniotic fluid volume.

Wang CC, Rogers MS

BJOG 1997;104(10): 1140 - 1144


Amnioinfusion for the prevention of meconium aspiration during labour.

Rogers MS, Lau TK, Wang CC, Yu KM

Aust NZ J Obstet Gyn 1996;36(4): 407 - 410


Cervical ripening before induction of labour in patients with an unfavorable cervix a comparative randomised study of the Atad ripener device, prostaglandin E2 vaginal pessary and prostaglandin E2.

Yuen PM, Pang HYY, Chung TKH, Chang AMZ

Aust NZ J Obstet Gyn 1996;36: 291 - 295


Fetal sex as a risk factor for fetal distress leading to abdominal delivery.

Lau TK, Chung TKH, Haines CJ, Chang AMZ

Aust NZ J Obstet Gyn 1996;36: 146 - 149


Lipid peroxidation in cord blood at birth.

Wang VW, Rogers MS, Chang AMZ, Pang CC

Am J Obstet Gynecol 1996;174(1): 62 - 65


A randomised double blind comparison of syntometrine and syntocinon in the management of the third stage of labour.

Yuen PM, Yim SF, Chang AMZ, Chan NST

BJOG 1995;102(5): 377 - 380


Computerised fetal heart rate analysis in labour - effect of sampling rate.

Chang AMZ, Sahota DS, Reed NN, James DK, Mohajer MP

Eur J Obstet Gyn R B 1995;59(2): 125 - 129


The prediction of fetal acidosis at birth by computerised analysis of intrapartum cardiotocography.

Chung TKH, Mohajer MP, Chang AMZ, Sahota DS, Yang ZJ

BJOG 1995;102(6): 454 - 460


A Perinatal Audit of Stillbirths in a Teaching Hospital in Hong Kong.

Lau TK, Li CY

Aust NZ J Obstet Gyn 1994;34(4): 416 - 421


Congenital listeriosis: Case reports and review of literature.

Leung TN, Cheung KL, Wong FWS

Asia Oceania J Obstet Gynaecol 1994;20(2): 173 - 177


General Anaesthesia for caesarean section in a patient with uncorrected complex cyanotic heart disease.

Rowbottom SJ, Gin T, Cheung LP

Anaesth Intens Care 1994;22(1): 74 - 78


Myomectomy in the treatment of postpartum haemorrhage.

Chung TKH, Stock AI, Chan MYM

BJOG 1994;101: 73 - 74


The influence of obstetric workload on caeserean section rate.

Chung TKH, Chang AMZ, Haines CJ, Rogers MS

Asia Oceania J Obstet Gynaecol 1994;20(3): 295 - 300


Randomised double blind placebo controlled comparison of ritodrine and hexoprenaline for tocolysis prior to external cephalic version at term.

Stock AI, Chung TKH, Rogers MS, Wong WM

Aust NZ J Obstet Gyn 1993;33(3): 265 - 268


Prelabour rupture of membranes at term and an unfavourable cervix; a randomised placebo controlled trial on early intervention with intravaginal prostaglandin E2 gel.

Chung TKH, Rogers MS, Chang AMZ

Aust NZ J Obstet Gyn 1992;32: 25 - 27


Perinatal asphyxia : A Bayesian analysis of prediction and prevention.

Chang AMZ, Rogers MS

J Obstet Gynaecol 1991;11: 34 - 40


Perinatal asphyxia: The role of intra-partum monitoring in prediction and prevention.

Rogers MS, Chang AMZ

J Obstet Gynaecol 1991;11: 34 - 40


Topical prostaglandin E2 gel for cervical ripening and closure of the ductus arteriosus in the newborn.

Sung RYT, Yin JA, Loong EPL, Fok TF, Lau JTF

Arch Dis Child 1990;65: 703 - 704


Neonatal thyrotrophin and mode of delivery.

Lao TTH, Panesar NS

BJOG 1989;96(10): 1224 - 1227


Perinatal asphyxia: Development of an 'Independence Bayes' computer prediction model.

Rogers MS, Chang AMZ

J Obstet Gynaecol 1989;10: 26 - 31


Single dose prophylactic antibiotics in caesarean sections.

Chan AC, Leung AKL, Chin RKH, Chang AMZ

Aust NZ J Obstet Gyn 1989;29(2): 107 - 109


The effect of labour on prolactin and cortisol concentrations in the mother and the fetus.

Lao TTH, Panesar NS

Eur J Obstet Gyn R B 1989;30(3): 233 - 238


A controlled trial on wound drainage in caesarean section.

Loong RL, Rogers MS, Chang AMZ

Aust NZ J Obstet Gyn 1988;28(4): 266 - 269


Changes in neonatal transcutaneous bilirubinometer index following intravenous fluid and oxytocin infusion during labour.

Loong EPL, Lao TTH, Chin RKH

Asia Oceania J Obstet Gynaecol 1988;14: 411 - 414


Psychogenic factors in hyperemesis gravidarum.

Tsoi PT, Chin RKH, Chang AMZ

Asia Oceania J Obstet Gynaecol 1988;14: 457 - 460


Association between prostaglandin E2 and placental abruption.

Leung AKL, Kwok P, Chang AMZ

BJOG 1987;94(10): 1001 - 1002


The importance of early prenatal diagnosis of thanatophoric dysplasia with respect to obstetric management.

Loong EPL

Eur J Obstet Gyn R B 1987;25: 145 - 152


Racial variations in the incidence of trisomy 21.

Rogers MS

BJOG 1986;93: 597 - 599


The need for chromosome diagnosis in the third trimester of pregnancy.

Loong EPL

J Obstet Gynaecol 1986;6: 215


The use of a microcomputer in the antenatal interview - a feasibility study.

Wong FWS

HK Pract 1986;8: 1650 - 1656


Ultrasound diagnosis of recurrence of Majewski Dwarfism.

Rogers MS, Cruickshank J

J.HK.Med.Assn. 1985;37: 95 - 97