Prof. Wang Yao, Max

Prof. Wang Yao, Max Research Assistant Professor

(852) 3505 1289

yaowang1@cuhk.edu.hk

Biography

Dr. Wang was awarded B.Sc. from Sun Yat-sen University in 2014 and he got his Ph.D. degree at the University of Hong Kong in 2019. He then gained a 3-year post-doctoral training in the Department of Medicine, University of Hong Kong.
He is now working in our department as a Research Assistant Professor from 2022.

Other Positions

Honorary Research Associate, Dept. of Medicine, University of Hong Kong
Honorary Research Fellow in Shenzhen Hospital, University of Hong Kong
Visiting Professor, Shaanxi University of Chinese Medicine

Research Interests

1) Biomarker discovery: to identify novel biomarkers for the prediction/diagnosis of gestational diseases;
2) Reproductive endocrinology: to investigate the role of hormones/cytokines in the development of pregnancy;
3) Gestational microbiome: to explore the role of the gut and vaginal microbiome for the onset of gestational disorders;
4) Lifestyle intervention during pregnancy: to improve the health of pregnant women with diet or exercise intervention.

Academic Award

2022 Young Investigator Oral Award - 24th Diabetes and Cardiovascular Risk Factors East Meets West Symposium

2021 Young Investigator ePoster Award - 15th International Symposium on Healthy Aging.

Funding Support

Health and Medical Research Fund (HMRF), No: 09201296; 2021; PI

National Natural Science Foundation of China’s (NSFC) Young Scientists Fund, No: 82200893; 2022; PI;

Health and Medical Research Fund (HMRF), No: 10212056; 2022; PI

OCRID: 0000-0003-0010-2819

Platelets in preeclampsia: an observational study of indices associated with aspirin nonresponsiveness, activation and transcriptional landscape Woldeamanuel GG, Tlaye KG, Wang X, Nguyen HL, Zhou Q, Wang Y, Leung BW, Wang Y, Poon CYL, Wang CC BMC, 2025 Jun;23:346

Effect of preconception antibiotics exposure on female reproductive health and pregnancy outcomes: a systematic review and meta-analysis Alemu BK, Wang CC, Li L, Zhu Z, Li Q, Wang Y eClinicalMedicine 2024 Dec:78; 102935

Exercise-changed gut mycobiome as a potential contributor to metabolic benefits in diabetes prevention: an integrative multi-omics study Wang Y, Chen J, Ni Y, Liu Y, Gao X, Tse MA, Panagiotou G, Xu A Gut Microbes. 2024 Jan-Dec;16(1):2416928

Melatonin Inhibits Endometriosis Growth via Specific Binding and Inhibition of EGFR Phosphorylation Li YR, Hung SW, Zheng X, Ding Y, Zhang T, Tan Z, Zhang R, Lin YZ, Song Y, Wang Y, Wang CC J Pineal Res. 2024 Nov;76(8):e70022

Breast milk application as a natural method for umbilical cord care: A community-label three-arm pilot clinical trial Alemu BK, Wondimagegn LY , Bazezew Y, Liyeh TM, Muluneh AA , Mihretie GN, Sema A , Endalifer ML , Azeze GG , Woldeamanuel GG , Tlaye KG , Lee WF , Wang Y , Wang CC Maternal-Fetal Medicine 2024 Oct; 6(4):203-210

Microbiota-targeted interventions and clinical implications for maternal-offspring health: An umbrella review of systematic reviews and meta-analyses of randomized controlled trials Alemu BK, Wu L, Azeze GG, Lau SL, Wang Y, Wang CC J Glob Health. 2024 Sep 13:14:04177

Preventive effect of prenatal maternal oral probiotic supplementation on neonatal jaundice (POPS Study): A protocol for the randomized double-blind placebo-controlled clinical trial Alemu BK, Lee MY, Leung MBW, Lee WF, Wang Y, Wang CC, Lau SL BMJ Open. 2024 Jun 8;14(6):e083641

Distinct molecular targets of ProEGCG from EGCG and superior inhibition of angiogenesis signaling pathways for treatment of endometriosis Hung SW, Gaetani M, Li Y, Tan Z, Zheng X, Zhang R, Ding Y, Man GCW, Zhang T, Song Y, Wang Y, Chung JPW, Chan TH, Zubarev RA, Wang CC Journal of Pharmaceutical Analysis 2024 Jan;14(1):100-114

Decreased serum soluble programmed cell death ligand-1 level as a potential biomarker for missed miscarriage Li Q, Chen C, Wu J, Poon LC, Wang CC, Li TC, Zhang T, Guo X, Song L, Wang X, Zhang Q, Ye Z, Yang Y, Lu J, Yao J, Ye D, Wang Y Hum Reprod. 2023 Nov 2;38(11):2128-2136

Effects of maternal probiotic supplementation on breast milk microbiome and infant gut microbiome and health: a systematic review and meta-analysis of randomized controlled trials Alemu BK, Azeze GG, Wu L, Lau SL, Wang CC, Wang Y Am J Obstet Gynecol MFM. 2023 Sep 1;5(11):101148

Pathophysiological insight into fatty acid-binding protein-4: multifaced roles in reproduction, pregnancy, and offspring health Shi Y, Wang CC, Wu L, Zhang Y, Xu A, Wang Y Int J Mol Sci. 2023 Aug 10;24(16):12655

The FGF21- Sirtuin 3 axis confers the protective effects of exercise against diabetic cardiomyopathy by governing mitochondrial integrity, L. Jin, L. Geng, L. Ying, L. Shu, K. Ye, R. Yang, Y. Liu, Y. Wang, Y. Cai, X. Jiang, Q. Wang, X. Yan. B. Liao, J. Liu, F. Duan, G. Sweeney, C. Woo, Y. Wang, Z. Xia, Q. Lian, A. Xu. Circulation. (2022) :101161CIRCULATIONAHA122059631. (IF=39.9; Q1, 1/336, Cardiology and Cardiovascular Medicine)

The human gut mycobiome and its potential as a regulator of the host's metabolic health. J. Chen, Y. Wang, A. Xu, G. Panagiotou. Vol. VI, Human and Animal Relationships, The Mycota series, Springer Nature publishing (Book chapter); Co-First author

A comprehensive evaluation of progestin-primed ovarian stimulation protocol in patients with or without PCOS undergoing in vitro fertilization Zhu J, Zhang J, Yang J, Li D, Wang C, Elizur SE, Zhao K, Kuang Y, Wang Y Reprod Biol. 2021 Aug 17;21(4):100540

Circulating fibroblast growth factor 21 as a potential biomarker for missed abortion in humans. Y. Yang*, J. Wu*, X. Wang*, J. Yao, K. S. Lao, Y. Qiao, Y. Xu, Y. Hu, Y. Feng, Y. Cui, S. Shi, J. Zhang, M. Liang, Y. Pan, K. Xie, K. Yan, Q Li#, D. Ye#, Y. Wang#. Fertility & Sterility. 116.4 (2021): 1040-1049, Corresponding author (IF=7.5; Q1, 3/63, Reproductive Medicine)

The relationship between serum hormone profiles and missed abortion in humans. Y Yang*, J. Wu*, X. Wang*, J. Yao, K. S. Lao, Y. Xu, Y. Hu, Y. Pan, Y. Feng, S. Shi, J. Zhang, Y. Qiao, Q. Li#, D. Ye#, Y. Wang#. Human Reproduction. Vol. 36, (2021) pp. 313-313; Corresponding author (IF=6.9; Q1, 2/63, Reproductive Medicine)

FGF21 mediates the anti-depressant effects of exercise by coordinating the crosstalk between central and peripheral organs. Y. Liu, S. Y. Yau, Q. Liang, Y. Wang, A. Xu, Human Behaviour and Brain. (2020) 1(1), 8-15 doi:10.37716/HBAB.2020010102.

Gut microbiome fermentation determines the therapeutic efficacy of exercise for diabetes prevention. Y. Liu*, Y. Wang*, Y. Ni*, C. K.Y Chong, K. S.L. Lam, Y. Wang, Z. Xia, D. Ye, J. Guo, M. A. Tse#, G. Panagiotou#, A. Xu#. Cell Metabolism. (2020) 31, 1-15. Co-First author (IF=31.4; Q1, 6/376, Molecular biology)

Gut microbiota-associated activation of TLR5 induces apolipoprotein A1 2 production in the liver J. H.C. Yiu, K-S Chan, J. Cheung, J. Li, Y. Liu, Y. Wang, W. W.L. Fung, J. Cai, S. W.M. Cheung, B. Dorweiler, E. Y.F. Wan, P. Tso, A. Xu, C. W. Woo, Circulation Research. 127.10 (2020): 1236-1252, (IF=23.2; Q1, 2/322, Cardiology and Cardiovascular Medicine)