The Chinese University of Hong Kong & Prince of Wales Hospital

Department of Obstetrics and Gynaecology
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Dr. Lee Ho Sze, Jacqueline

Dr. Lee Ho Sze, Jacqueline Consultant, Clinical Associate Professor (honorary)
(852) 3505 2748 jaclee@cuhk.edu.hk

Qualifications

MBChB (CUHK), MRCOG, MHKCOG, FHKCOG, FHKAM(O&G), Cert HKCOG (GynOnc), MSc in Medical Genetics

Biography

Dr. LEE Ho Sze Jacqueline graduated from The Chinese University of Hong Kong. After her specialty training in Obstetrics and Gynaecology, she received the Hospital Authority Corporate Scholarship and undergone overseas training in gynaecological oncology, particularly in the area of minimally invasive surgery, robotic surgery and radical debulking operations, in 1) Gynaecological Oncology Unit, Nuffield Department of Women’s Reproduction Health, University of Oxford, United Kingdom; 2) Gynaecological Oncology Department, Imperial College Healthcare NHS, United Kingdom; 3) Department of Gynecologic Oncology, Centre Oscar Lambret, France.

Dr. Lee is a gynaecological oncology subspecialist of the Hong Kong College of Obstetricians and Gynaecologists and specializes in providing care for patients with gynaecological tumours. She is an accredited colposcopist and trainer in colposcopy of the HKCOG, a robotic surgery surgeon and holds a Master of Science in Medical Genetics degree. Dr. Lee is also actively involved in the education of the medical profession and general public. She is the President of the Hong Kong Society for Colposcopy and Cervical Pathology.

Other Positions

President of the Hong Kong Society for Colposcopy and Cervical Pathology
Board member of the HKCOG Gynaecological Oncology Subspecialty Board

Clinical & Research Interests

Endometrial cancer, Sentinel lymph node mapping, Cervical cancer, Ovarian cancer, Lower genital tract disorders, Minimally invasive surgery, Colposcopy, Robotic surgery

1
Mature Cystic Teratoma: An Integrated Review Cong L, Wang S, Yeung SY, Lee JHS, Chung JPW, Chan DYL Int. J. Mol. Sci. 2023, 24(7), 6141
2
Smear detected cervicovaginal melanoma following negative screening— a cautionary tale of rapidly developing malignancy of the lower female genital tract Ng JKM, Li JJX, Lee JHS Cytopathology. 2021 Nov;32(6):819-822
3
Long-Term Survival and Clinicopathological Implications of DNA Mismatch Repair Status in Endometrioid Endometrial Cancers in Hong Kong Chinese Women Lee JHS, Li JJX, Chow C, Chan RCK, Kwan JSH, Lau TS, To KF, Yim SF, Yeung SY, Kwong J Biomedicines. 2021 Oct 4;9(10):1385
4
Intrauterine fetal death followed by shoulder dystocia and birth by modified posterior axillary sling method: a case report Leung TY, Kwan AHW, Hui ASY, Lee JHS. BMC Pregnancy Childbirth. 2021 Oct 3;21(1):672.  doi: 10.1186/s12884-021-04126-4.
5
Dissection of PIK3CA Aberration for Cervical Adenocarcinoma Outcomes Chung TKH, Doran G, Cheung TH, Yim SF, Yu MY, Worley MJ, Elias KM, Thorner AR, Pedamallu CS, Ojesina AI, Lau KM, Ducar MD, Wong RRY, Wang VVW, Nag A, Wollison BM, Dalgarno A, Lee JHS, Yeung SY, Wong L, Horowitz NS, Davis MR, Leung SOA, Mu Y, Mok SC, Chan PKS, Lawrence MS, Crum CP, Chiu RWK, Berkowitz RS, Wong YF Cancers (Basel). 2021 Jun 28;13(13):3218
6
Short-form thymic stromal lymphopoietin (sFTSLP) is the predominant isoform expressed by gynaecologic cancers and promotes tumour growth Chan LKY, Lau TS, Chung KY, Tam C, Cheung TH, Yim SF, Lee JHS, Leung RWT, Qin J, Or YYY, Lo KW, Kwong J Cancers 2021 Feb;13(5):980
7
2020 Hong Kong College of Obstetricians and Gynaecologists guideline on investigations of premenopausal women with abnormal uterine bleeding Lee JHS, Cheng EOL, Choi KM, Ngu SF, Cheung RYK Hong Kong Med J. 2020 Dec;26(6):520-525
8
Paclitaxel Induces Immunogenic Cell Death in Ovarian Cancer via TLR4/IKK2/SNARE-Dependent Exocytosis Lau TS, Chan LKY, Man GCW, Wong ECH, Lee JHS, Yim SF, Cheung TH, Iain M, Kwong J Cancer Immunol Res. 2020 Aug;8(8):1099-1111
9
Trichoblastic Carcinosarcoma Arising From the Vagina: A Case Report With Comprehensive Immunophenotypic Analysis Li JJX, Ng JKM, Choi PCL, Lee JHS, Yu MY Int J Surg Pathol. 2020 Jun;28(4):440-446
10
Trichoblastic Carcinosarcoma Arising From the Vagina: A Case Report With Comprehensive Immunophenotypic Analysis. Li J.J.X., Ng J.K.M., Choi P.C.L., Lee J.H.S., Yu M. International Journal of Surgical Pathology, 2020 Jun;28(4), 440-446.
11
Uterine carcinosarcoma with alpha-fetoprotein-producing hepatoid component: a case report and literature review Li JJX, Lee JHS, Chan VTC, Yu MY Case Rep Pathol. 2018 Jun 11;2018:3972353, 5 pages
12
The performance of pre-operative MRI in service-based centers in diagnosing cervical invasion by endometrial carcinoma Lee JHS, Cheung TH, Yim SF European Journal of Gynaecological Oncology 2018 ;39(1): 112-118
13
A loop of cancer-stroma-cancer interaction promotes peritoneal metastasis of ovarian cancer via TNFα-TGFα-EGFR Lau TS, Chan LKY, Wong ECH, Hui CWC, Sneddon K, Cheung TH, Yim SF, Lee JHS, Yeung CSY, Chung TKH, Kwong J Oncogene. 2017 Jun 22;36(25):3576-3587
14
Levator ani muscle avulsion is a risk factor for vaginal pessary expulsion within 1 year for pelvic organ prolapse. Cheung RY, Lee JHS, Lee LL, Chung TK, Chan SS. Ultrasound Obstet Gynecol. 2017 Dec;50(6):776-780.
15
Antenatal Surgical Management for Ovarian Cysts: 13 Years’ Experience Yeung SY, Lee JHS Hong Kong J Gynaecol Obstet Midwifery 2017; 17(1):18-23
16
Levator Ani Muscle Avulsion is a Risk Factor for Expulsion within 1 Year of Vaginal Pessary Placed for Pelvic Organ Prolapse. Cheung RYK, Lee JHS, Lee LL, Chung TKH, Chan SS. Ultrasound Obstet Gynecol 2017;50:776-780
17
The performance of preoperative MRI in service-based centers in diagnosing deep myometrial invasion by endometrial carcinoma Lee JHS, Cheung TH, Yim SF European Journal of Gynaecological Oncology 2017;38(5):667-674
18
Vaginal Pessary in Women with Symptomatic Pelvic Organ Prolapse: A Randomized Controlled Trial. Cheung RYK, Lee JHS, Lee LLL, Chung TKH, Chan SSC Obstet Gynecol Jul 2016;128(1): 73 - 80
19
A Pilot Study of Urine Cytokines in Ketamine-associated Lower Urinary Tract Symptoms. Cheung RYK, Lee JHS, Chan SSC, Lui WT, Choy KW Int Urogynecol J 2014;25(12): 1715 - 1719
20
Placental and fetal candidiasis associated with intrauterine contraceptive device in situ. Lee HS, Lo AW. Pathology. 2011 Apr;43(3):276-7.
21
Urinary Symptoms and Impaired Quality of Life in Female Ketamine Users: Persistence after Cessation of Use. Cheung RYK, Chan SSC, Lee JHS, Pang WL, Choy KW, Chung TKH Hong Kong Med J 2011;17(4): 267 - 273