Dr. YIM So Fan

Current Position:
Consultant
Clinical Associate Professor (honorary)

Office Phone:
(852) 3505 2801

E-mail:
sfyim@cuhk.edu.hk

Qualifications:
MBChB, MD, FRCOG, FHKCOG,
FHKAM(O&G)

1Prevalence and Impact of Hepatitis B Virus Infection in Ovarian Cancer Patients in an Endemic Area – a Retrospective Cohort Study
Wong L, Cheung TH, Yim SF, Lao TT
J Viral Hepat. 2020 May;27(5):520-525
2Liquid biopsy of HPV DNA in cervical cancer
Cheung TH, Yim SF, Yu MY, Worley MJ Jr, Fiascone SJ, Chiu RWK, Lo KWK, Siu NSS, Wong MCS, Yeung ACM, Wong RRY, Chen ZG, Elias KM, Chung TKH, Berkowitz RS, Wong YF, Chan PKS
J Clin Virol. 2019 May;114:32-36
3The performance of pre-operative MRI in service-based centers in diagnosing cervical invasion by endometrial carcinoma
Lee JHS, Cheung TH, Yim SF
European Journal of Gynaecological Oncology  2018 ;39(1): 112-118 
4The performance of preoperative MRI in service-based centers in diagnosing deep myometrial invasion by endometrial carcinoma
Lee JHS, Cheung TH, Yim SF
European Journal of Gynaecological Oncology 2017;38(5):667-674
5Osteopontin Fragments with Intact Thrombin-Sensitive Site Circulate in Cervical Cancer Patients
Leung DT, Lim PL, Cheung TH, Wong RR, Yim SF, Ng MH, Tam FC, Chung TKH, Wong YF
PLoS One. 2016 Aug 5;11(8):e0160412
6Liquid biopsy of PIK3CA mutations in cervical cancer in Hong Kong Chinese women
Chung TKH, Cheung TH, Yim SF, Yu MY, Chiu RWK, Lo KWK, Lee IPC, Wong RRY, Lau KKM, Wang VW, Worley MJ Jr, Elias KM, Fiascone SJ, Smith DI, Berkowitz RS, Wong YF
Gynecol Oncol. 2017 Aug;146(2):334-339
7A loop of cancer-stroma-cancer interaction promotes peritoneal metastasis of ovarian cancer via TNFα-TGFα-EGFR
Lau TS, Chan LKY, Wong ECH, Hui CWC, Sneddon K, Cheung TH, Yim SF, Lee JHS, Yeung CSY, Chung TKH, Kwong J
Oncogene. 2017 Jun 22;36(25):3576-3587
8Genomic Aberrations in Cervical Adenocarcinomas in Hong Kong Chinese Women.
Chung TKH, Hummelen PV, Chan PKS, Cheung TH, Yim SF, Yu MMY, Ducar MD, Thorner AR, MacConaill LE, Doran G, Pedamallu CS, Ojesina AI, Wong RRY, Wang VW, Freeman SS, Lau TS, Kwong J, Chan LKY, Fromer M, May T, Worley MJJR, Esselen KM, Elias KM, Lawrence M, Lawrence M, Getz Gad, Smith DI, Crum CP, Meyerson M, Berkowitz RS, Wong YF
Int J Cancer 2015;137(4): 776 - 783
9Cancer Cell-derived Lymphotoxin Mediates Reciprocal Tumour¡VStromal Interactions in Human Ovarian Cancer by Inducing CXCL11 in Fibroblasts.
Lau TS, Chung TKH, Cheung TH, Chan LKY, Cheung WH, Yim SF, Siu NSS, Lo KW, Yu MMY, Kulbe H, Balkwill FR, Kwong J
J Pathol 2014;232(1): 43 - 56
10Attribution of Human Papillomavirus Types to Cervical Intraepithelial Neoplasia and Invasive Cancers in Southern China.
Chan PKS, Cheung TH, Li WH, Yu MMY, Chan MYM, Yim SF, Ho WCS, Yeung ACM, Ho KM, Ng HK
Int J Cancer 2012;131(3): 692 - 705
11Dysregulated microRNAs in the Pathogenesis and Progression of Cervical Neoplasm.
Cheung TH, Man MKN, Yu MMY, Yim SF, Siu NSS, Lo KWK, Doran G, Wong RRY, Wang VW, Smith DI, Worley MJJR, Berkowitz RS, Chung TKH, Wong YF
Cell Cycle 2012;11(15): 2876 - 2884
12Dysregulation of microRNA-204 Mediates Migration and Invasion of Endometrial Cancer by Regulating FOXC1.
Chung TKH, Lau TS, Cheung TH, Yim SF, Lo KWK, Siu NSS, Chan LKY, Yu MMY, Kwong J, Doran G, Barroilhet LM, Ng ASW, Wong RRY, Wang VW, Mok SC, Smith DI, Berkowitz RS, Wong YF
Int J Cancer 2012;130(5): 1036 - 1045
13Hysterectomy for Recurrent Postmenopausal Bleeding Revisited: Missed Sclerosing Stromal Ovarian Tumour.
Chung JPW, Cheung ECW, Yim SF, Mak SM
Hong Kong Med J 2012;18(4): 338 - 339
14CHD5 Downregulation Associated with Poor Prognosis in Epithelial Ovarian Cancer.
Wong RRY, Chan LKY, Tsang PT, Lee CWS, Cheung TH, Yim SF, Siu NSS, Lee SNC, Yu MMY, Chim SSC, Wong YF, Chung TKH
Gynecol Obstet Inves 2011;72(3): 203 - 207
15Clinical Use of Laparoscopic Ultrasonography in Detecting Nodal Metastasis in Advanced-Stage Cervical Carcinoma.
Cheung TH, Lo KWK, Yim SF, Siu NSS, Yu MMY
Int J Gynecol Obstet 2011;112(2): 154 - 158
16Debulking Metastatic Pelvic Nodes before Radiotherapy in Cervical Cancer Patients: A Long-term Follow-up Result.
Cheung TH, Lo KWK, Yim SF, Yau SH, Yu MMY, Yeung WK
Int J Clin Oncol 2011;16(5): 546 - 552
17Risk Factors for Squamous Intraepithelial Lesions in Systemic Lupus Erythematosus: A Prospective Cohort Study.
TAM LS, Chan PKS, Ho SC, Yu MMY, Yim SF, Cheung TH, Wong MCS, Cheung JLK, Li EKM
Arthritis Care Res 2011;63(2): 269 - 276
18The Technique of Laparoscopic Pelvic Ultrasonography for Metastatic Lymph Node.
Cheung TH, Lo KWK, Yim SF, Ho SSY, Yu MMY, Yang WT
J Laparoendose Adv Surg Tech 2011;21(1): 61 - 65
19Clinical Study of Quantitative Diagnosis of Early Cervical Cancer Based on the Classification of Acetowhitening Kinetics.
Wu T, Cheung TH, Yim SF, Qu JY
J Biomed Opt 2010;15(2): 026001
20Natural History of Cervical Papilloma Virus Infection in Systemic Lupus Erythematosus - A Prospective Cohort Study.
TAM LS, Chan PKS, Ho SC, Yu MMY, Yim SF, Cheung TH, Wong MCS, Li EKM
J Rheumatol 2010;37(2): 330 - 340
21Cryotherapy as the treatment modality of postcoital bleeding: a randomised clinical trial of efficacy and safety.
Kong GWS, Yim SF, Cheung TH, Chung TKH
Aust NZ J Obstet Gyn 2009;49(5): 517 - 524
22Dysregulated microRNAs and their predicted targets associated with endometrioid endometrial adenocarcinoma in Hong Kong women.
Chung TKH, Cheung TH, Huen NY, Wong KWY, Lo KWK, Yim SF, Siu NSS, Wong YM, Tsang PT, Pang MW, Yu MMY, To KF, Mok SC, Wang VW, Li C, Cheung AYK, Doran G, Birrer MJ, Smith DI, Wong YF
Int J Cancer 2009;124(6): 1358 - 1365
23Optical Imaging of Cervical Precancerous Lesions Based on Active Stereo Vision and Motion Tracking.
Wu TT, Cheung TH, Yim SF, Qu JY
Opt Express 2008;16(15): 11224 - 11230
24Association between HLA-DRB1 polymorphism, high-risk HPV infection and cervical neoplasia in southern Chinese.
Chan PKS, Cheung TH, Lin CK, Siu NSS, Yim SF, Lo KWK, Cheung JLK, Tam AOY, Tang JWT
J Med Virol 2007;79(7): 970 - 976
25HLA-DQB1 polymorphisms and risk for cervical cancer: A case-control study in a southern Chinese population.
Chan PKS, Cheung JLK, Cheung TH, Lin CK, Siu NSS, Yu MMY, Tang JWT, Lo KWK, Yim SF, Wong YF, To KF, Ng HK, Chung TKH
Gynecol Oncol 2007;105(3): 736 - 741
26Identification of molecular markers and signaling pathway in endometrial cancer in Hong Kong Chinese women by genome-wide gene expression profiling.
Wong YF, Cheung TH, Lo KWK, Yim SF, Siu NSS, Chan CS, Ho TWF, Wong KWY, Yu MMY, Wang VW, Li C, Gardner GJ, Bonome T, Johnson WB, Smith DI, Chung TKH, Birrer MJ
Oncogene 2007;26(13): 1971 - 1982
27Is aortic lymphadenectomy necessary in the management of endometrial carcinoma?
Siu NSS, Lo KWK, Cheung TH, Yim SF, Chung TKH
Eur J Gynaecol Oncol 2007;28(2): 98 - 102
28Profile of Viral Load, Integration, and E2 Gene Disruption of HPV58 in Normal Cervix and Cervical Neoplasia.
Chan PKS, Cheung JLK, Cheung TH, Lo KWK, Yim SF, Siu NSS, Tang JWT
J Infect Dis 2007;196(6): 868 - 875
29Biases in human papillomavirus genotype prevalence assessment associatedwith commonly used consensus primers.
Chan PKS, Cheung TH, Tam AOY, Lo KWK, Yim SF, Yu MMY, To KF, Wong YF, Cheung JLK, Chan DPC, Hui M, Ip M
Int J Cancer 2006;118(1): 243 - 245
30Detection of microsatellite instability in endometrial cancer: advantages of a panel of five mononucleotide repeats over the National Cancer Institute panel of markers.
Wong YF, Cheung TH, Lo KWK, Yim SF, Chan LKY, Buhard O, Duval A, Chung TKH, Hamelin R
Carcinogenesis 2006;27(5): 951 - 955
31Gene expression pattern associated with radiotherapy sensitivity in cervical cancer.
Wong YF, Sahota DS, Cheung TH, Lo KWK, Yim SF, Chung TKH, Chang AMZ, Smith DI
Cancer J 2006;12(3): 189 - 193
32Genome-wide gene expression profiling of cervical cancer in Hong Kong women by oligonucleotide microarray.
Wong YF, Cheung TH, Tsao GSW, Lo KWK, Yim SF, Wang VW, Heung MS, Chan CS, Chan LKY, Ho TWF, Wong KWY, Li C, Guo Y, Chung TKH, Smith DI
Int J Cancer 2006;118(10): 2461 - 2469
33HLA-B alleles, high-risk HPV infection and risk for cervical neoplasia in southern Chinese women.
Chan PKS, Cheung JLK, Cheung TH, Lin CK, Tam AOY, Chan DPC, Zhou DXM, Lo KWK, Yim SF, Siu NSS
Int J Cancer 2006;118(6): 1430 - 1435
34Is common iliac lymph node dissection necessary in early stage cervical carcinoma?
Siu NSS, Cheung TH, Lo KWK, Yim SF, Chung TKH
Gynecol Oncol 2006;103(1): 58 - 61
35Multipopulation analysis of polymorphisms in five mononucleotide repeats used to determine the microsatellite instability status of human tumors.
Buhard O, Cattaneo F, Wong YF, Yim SF, Friedman E, Flejou JF, Duval A, Hamelin R
J Clin Oncol 2006;24(2): 241 - 251
36Serum Vascular Endothelial Growth Factor as a Possible Indicator of Arterial Reactivity in Postmenopausal Women.
Lam PM, Yim SF, Chung TKH, Haines CJ
Gynecol Endocrinol 2006;22(8): 460 - 464
37Clinicopathologic significance of loss of heterozygosity on chromosome 1 in cervical cancer.
Cheung TH, Lo KWK, Yim SF, Poon CS, Cheung AYK, Chung TKH, Wong YF
Gynecol Oncol 2005;96: 510 - 515
38Dose effects of progesterone in add-back therapy during GnRHa treatment.
Cheung TH, Lo KWK, Yim SF, Lam CWK, Lau Edith MC, Haines CJ
J Reprod Med 2005;50(1): 35 - 40
39Risk Association between Human Leukocyte Antigen¡VA Allele and High-Risk Human Papillomavirus Infection for Cervical Neoplasia in Chinese Women.
Chan DPC, Cheung TH, Tam AOY, Cheung JLK, Yim SF, Lo KWK, Siu NSS, Zhou DXM, Chan PKS
J Infect Dis 2005;192(10): 1749 - 1756
40Study of dynamic process of acetic acid induced-whitening in epithelial tissues at cellular level.
Wu T, Qu JY, Cheung TH, Yim SF, Wong YF
Opt Express 2005;13(13): 4963 - 4973
41Transcriptional repression of WEE1 by Kruppel-like factor 2 is involved in DNA damage-induced apoptosis.
Wang F, Zhu Y, Huang Y, McAvoy S, Johnson WB, Cheung TH, Chung TKH, Lo KWK, Yim SF, Yu MMY, Ngan HYS, Wong YF, Smith DI
Oncogene 2005;24(24): 3875 - 3885
42Correlation of transvaginal ultrasound findings and serum beta-hCG level in cervical pregnancy.
Yim SF, Lo KWK, Chan SSC, Cheung TH
Ultrasound Obst Gyn 2004;24(6): 694 - 695
43Epigenetic and genetic alternation ofPTEN in cervical neoplasm.
Cheung TH, Lo KWK, Yim SF, Chan LKY, Heung MS, Chan CS, Cheung AYK, Chung TKH, Wong YF
Gynecol Oncol 2004;93(3): 621 - 627
44Prospective self-controlled study on prevention of hysteroscopic dissemination in endometrial carcinoma.
Lo KWK, Cheung TH, Yim SF, Yu MMY, Chan Louis YS, Chung TKH
Int J Gynecol Cancer 2004;14(5): 921 - 926
45Raloxifene therapy in postmenopausal women is associated with a significant reduction in the concentration of serum vascular endothelial growth factor.
Lam PM, Yim SF, Briton Jones C , Chung TKH, Haines CJ
Fertil Steril 2004;81(2): 393 - 397
46A prospective, randomized, placebo-controlled study of the dose effect of oral oestradiol on bone mineral density in postmenopausal Chinese women.
Haines CJ, Yim SF, Chung TKH, Lam CWK, Lau Edith MC, Ng MHL, Chin RKH, Lee DTS
Maturitas 2003;45(3): 169 - 173
47A prospective, randomized, placebo-controlled study of the dose effect of oral oestradiol on menopausal symptoms, psychological well being, and quality of life in postmenopausal Chinese women.
Haines CJ, Yim SF, Chung TKH, Lam CWK, Lau Edith MC, Ng MHL, Chin RKH, Lee DTS
Maturitas 2003;44(3): 207 - 214
48Expression Genomics of Cervical Cancer: Molecular Classification and Prediction of Radiotherapy Response by DNA Microarray.
Wong YF, Selvanayagam ZE, Wei N, Porter J, Vittal R, Hu R, Yap SF, Kita T, Lin AW, Cheung TH, Lo KWK, Yim SF, Yip SK, Leung TN, Siu NSS, Chan LKY, Chan CS, Kong T, Kutlina E, McKinnon RD, Denhardt DT, Chin KV, Chung TKH
Clin Cancer Res 2003;9(15): 5486 - 5492
49Patients with Systemic Lupus Erythematosus Show Increased Platelet Activation and Endothelial Dysfunction Induced by Acute Hyperhomocysteinemia.
TAM LS, Fan B, Li EKM, Thomas GN, Yim SF, Haines CJ, Thomlinson B
J Rheumatol 2003;30(7): 1479 - 1484
50The role of microsatellite instability in cervical intraepithelial neoplasia and squamous cell carcinoma of the cervix.
Wong YF, Cheung TH, Poon KY, Wang VW, Li JCB, Lo KWK, Yim SF, Yu MMY, Lahr G, Chung TKH
Gynecol Oncol 2003;89(3): 434 - 439
51The value of pelvic and para-aortic lymphadenectomy in endometrial cancer to avoid unnecessary radiotherapy.
Lo KWK, Cheung TH, Yu MMY, Yim SF, Chung TKH
Int J Gynecol Cancer 2003;13(6): 863 - 869
52Cervical Intraepithelial Neoplasia is Associated with Increased Polyamine Oxidase and Diamine Oxidase Concentrations in Cervical Mucus.
Rogers MS, Yim SF, Li KC, Wang CC, Arumanayagam M
Gynecol Oncol 2002;84(3): 383 - 387
53Entrapment of Viable Trophoblastic Tissue in a Uterine Hematoma After Surgical Evacuation. A Case Report.
Lam PM, Yim SF, Leung TN
J Reprod Med 2002;47(2): 170 - 172
54Expression of apoptotic regulators and their significance in cervical cancer.
Chung TKH, Cheung TH, Lo KWK, Yim SF, Yu MMY, Krajewski S, Reed JC, Wong YF
Cancer Lett 2002;180(1): 63 - 68
55Hysteroscopic dissemination of endometrial carcinoma using carbon dioxide and normal saline: a retrospective study.
Lo KWK, Cheung TH, Yim SF, Chung TKH
Gynecol Oncol 2002;84(3): 394 - 398
56Aberrant expression of p21WAF1/CIP1 and p27KIP1 in cervical carcinoma.
Cheung TH, Lo KWK, Yu MMY, Yim SF, Poon CS, Chung TKH, Wong YF
Cancer Lett 2001;172(1): 93 - 98
57Alteration of cyclin D1 and CDK4 gene in carcinoma of uterine cervix.
Cheung TH, Yu MMY, Lo KWK, Yim SF, Chung TKH, Wong YF
Cancer Lett 2001;166(2): 199 - 206
58Anti-ischemic Action of Estrogen-Progestogen Continuous Combined Hormone Replacement Therapy in Postmenopausal Women with Established Angina Pectoris: A Randomized, Placebo-Controlled, Double-Blind, Parallel-Group Trial.
Sanderson JE, Haines CJ, Yeung L, Yip GWK, Tang K, Yim SF, Jorgensen LN, Woo J
J Cardiovasc Pharm 2001;38(3): 372 - 383
59Dose-finding study for the use of long-acting gonadotrophin-releasing hormone analogues prior to ovarian stimulation for IVF.
Yim SF, Lok IH, Cheung LP, Briton Jones C , Chiu TTY, Haines CJ
Hum Reprod 2001;16(3): 492 - 494
60Preoperative Hysteroscopic Assessment of Cervical Invasion by Endometrial Carcinoma: A Retrospective Study.
Lo KWK, Cheung TH, Yim SF, Chung TKH
Gynecol Oncol 2001;82(2): 279 - 282
61Randomized double-masked comparison of radially expanding access device and conventional cutting tip trocar in laparoscopy.
Yim SF, Yuen PM
Obstet Gynecol 2001;97(3): 435 - 438
62The effect of continuous combined hormone replacement therapy on arterial reactivity in postmenopausal women with established angina pectoris.
Haines CJ, Yim SF, Sanderson JE
Atherosclerosis 2001;159(2): 467 - 470
63The effects of follicular fluid and platelet-activating factor on motion characteristics of poor-quality cryopreserved human sperm.
Briton Jones C , Yeung QSY, Tjer GCC, Chiu TTY, Cheung LP, Yim SF, Lok IH, Haines CJ
J Assist Reprod Gen 2001;18(3): 165 - 170
64Whole blood mercury concentrations in sub-fertile men in Hong Kong.
Leung TY, Choy CMY, Yim SF, Lam CWK, Haines CJ
Aust NZ J Obstet Gyn 2001;41(1): 75 - 77
65A prospective randomized controlled study of the effect of hormone replacement therapy on peripheral blood flow velocity in postmenopausal women.
Lau TK, Wan D, Yim SF, Sanderson JE, Haines CJ
Fertil Steril 1998;70(2): 284 - 288
66Intramyometrial abscess complicating pregnancy: a report of two cases.
Fung TY, Yim SF, Fung HYM
J Reprod Med 1998;43(11): 1002 - 1004
67Metabolic and inflammatory responses after laparoscopic and abdominal hysterectomy.
Yuen PM, Mak TWL, Yim SF, Ngan Kee WD, Lam CWK, Rogers MS, Chang AMZ
Am J Obstet Gynecol 1998;179(1): 1 - 5
68Prospective randomized study of the effect of 'add-back' hormone replacement on vascular function during treatment with gonadotropin releasing hormone agonists.
Yim SF, Lau TK, Sahota DS, Chung TKH, Chang AMZ, Haines CJ
Circulation 1998;98: 1631 - 1635
69C-myc mutation detected by polymerase chain reaction - heteroduplex in cervical cancer.
Wong YF, Rogers MS, Cheung TH, Yim SF, Chang AMZ
Gynecol Obstet Inves 1997;44(2): 136 - 140
70Failed Caesarean section : an Obstetrician's nightmare.
Yuen PM, Yim SF
Aust NZ J Obstet Gyn 1997;37(4): 472 - 473
71p16INK4 and p15INK4B Alterations in Primary Gynecologic Malignancy.
Wong YF, Chung TKH, Cheung TH, Nobori T, Yim SF, Lai WH, Yu AL, Diccianni MB, Li TZ, Chang AMZ
Gynecol Oncol 1997;65: 319 - 324
72Iatrogenic cardiac tamponade during pregnancy.
Yim SF, Lam SK, Haines CJ
Aust NZ J Obstet Gyn 1996;36: 205 - 206
73A prospective study of the microbiological environment of the genitourinary tract in Hong Kong Chinese women during pregnancy.
Yim SF, Chung TKH, Haines CJ, Lyon DJ
Aust NZ J Obstet Gyn 1995;35(2): 178 - 181
74A randomised double blind comparison of syntometrine and syntocinon in the management of the third stage of labour.
Yuen PM, Yim SF, Chang AMZ, Chan NST
BJOG 1995;102(5): 377 - 380
75Misdiagnosis of an intersitial ectopic pregnancy after unilateral salpingectomy.
Yim SF, Fung HYM, To KF
Aust NZ J Obstet Gyn 1995;36(1): 80 - 82