Academic Publications in Gynae-endoscopy

 

 

The Gynae-endoscopy Team has both clinical and basic research interests not only in Gynecological Endoscopic surgery, but also in endometriosis, uterine fibroids  as well as postmenopausal bleeding.   The following are the highlights of publications.

 

Endometriosis

Current hormonal and surgical treatment for endometriosis still cannot avoid undesired endocrine side effects and disease recurrence. We are the first group studying therapeutic effects of green tea on endometriosis (Xu et al Hum Reprod 2009). We showed a green tea polyphenol, epigallocatchin-3-gallate (EGCG), as a potent anti-angiogenesis agent for endometriosis (Xu et al Fertil Steril 2011, Xu et al Angiogenesis 2013a). We also had patented an acetylated EGCG as prodrug of EGCG, pro-EGCG, and successfully achieved higher bioavailability and better inhibition in angiogenesis and growth of endometriosis (Wang et al Angiogenesis 2013b).

 

Postmenopausal Bleeding

Endometrial cancer is currently the most common malignancy of female genital tract in Hong Kong, up to 90 % of women presenting as postmenopausal bleeding (PMB). We set up One- Stop PMB Clinic since 2002 aiming to streamline the management of PMB women. We found the E. coli, B. fragilis, and Enterococcus are the commonest microorganisms isolated in PMB women with uterine collection ( Yeung et al 2014 ). From our study ( n=4383 ), the sensitivity on detecting endometrial malignancy using endometrial thickness 3-, 4-, 5-mm cut-offs were 97%, 94.1% and 93.5% respectively . The specificity were 45.3%, 66.8% and 74% respectively (Wong et al BJOG 2016).

 

Uterine Fibroid

Our studies have found that the transcervical intralesional injection of vasopressin is useful in decrease fluid absorption, blood loss in hysteroscopic myomectomy patients (Wong et al J Laparoendose Adv Surg Tech 2013; Wong et al Obstetrics and Gynecology 2014). Apart from the surgical treatment, we are also liaised with the Department of Imaging and Interventional Radiology to provide alternative treatments to uterine fibroids, like uterine artery embolization, high-intensity focused ultrasound, especially to women failed medical treatment (Leung et al J Ultrasound Med 2014).

 

 

 

 

 

 

The following are selected publications in endometriosis, uterine fibroids and postmenopausal bleeding.

 


Endometriosis

 

 

 


Postmenopausal Bleeding

 

 

 


Uterine fibroid

 

 

 

 

1Development and Validation of Prediction Models for Endometrial Cancer in Postmenopausal Bleeding.
Wong ASW, Cheung ECW, Fung LWY, Lao TTH, Mol BWJ, Sahota DS
Eur J Obstet Gyn R B 2016;203: 220 - 224
2Reappraisal of Endometrial Thickness for the Detection of Endometrial Cancer in Postmenopausal Bleeding: A Retrospective Cohort.
Wong ASW, Lao TTH, Cheung ECW, Yeung SW, Fan HL, Ng PS, Yuen PM, Sahota DS
BJOG 2016;123(3): 439 - 446
3Transcervical Intralesional Vasopressin Injection Compared with Placebo in Hysteroscopic Myomectomy.
Wong ASW, Cheung ECW, Yeung SW, Fan HL, Leung TY, Sahota DS
Obstet Gynecol 2014;124(5): 897 - 903
4Transcervical Intralesional Vasopressin Injection in Hysteroscopic Myomectomy-Description of a New Technique.
Wong ASW, Cheung ECW, Leung VKT, Yeung SW, Leung TY, Fung TY
J Laparoendose Adv Surg Tech 2013;23(3): 258 - 262
5Comparison of the different types of "laparoscopic total hysterectomy".
Leung SW, Chan CS, Lo LSF, Pang CP, Pun TC, Yuen PM
J Minim Invasive Gynecol 2007;14(1): 91 - 96
6A cost-utility analysis of hysterectomy, endometrial resection and ablation and medical therapy for menorrhagia.
You JHS, Sahota DS, Yuen PM
Hum Reprod 2006;21(7): 1878 - 1883
7Postablation-tubal sterilization syndrome following thermal balloon endometrial ablation.
Leung PL, Yuen PM
Acta Obstet Gyn Scan 2006;85(4): 504 - 505
8Isolated vulval varicosity in the non-pregnant state: a case report with review of the treatment options.
Leung SW, Leung PL, Yuen PM, Rogers MS
Aust NZ J Obstet Gyn 2005;45(3): 254 - 256
9Outcome in laparoscopic management of persistent adnexal mass during the second trimester of pregnancy.
Yuen PM, Ng PS, Leung PL, Rogers MS
Surg Endosc 2004;18(9): 1354 - 1357
10Comparison of Peritoneal Oxidative Stress During Laparoscopy and laparostomy.
De Souza A, Rogers MS, Wang CC, Yuen PM, Ng PS
J Am Assoc Gyn Lap 2003;10(1): 65 - 74
11Hysteroscopic appearance of the endometrial cavity following thermal balloon endometrial ablation.
Leung PL, Tam WH, Yuen PM
Fertil Steril 2003;79(5): 1226 - 1228
12Intrauterine pathology in women with abnormal uterine bleeding taking hormone replacement therapy.
Leung PL, Tam WH, Kong GWS, Yuen PM
J Am Assoc Gyn Lap 2003;10(2): 260 - 262
13Life-table analysis of the success of thermal balloon endometrial ablation in the treatment of menorrhagia.
Lok IH, Leung PL, Ng PS, Yuen PM
Fertil Steril 2003;80(5): 1255 - 1259
14Measurement of Trocar Insertion Force Using a Piezoelectric Transducer.
Ng PS, Sahota DS, Yuen PM
J Am Assoc Gyn Lap 2003;10(4): 534 - 538
15Successful treatment of ruptured interstitial pregnancy with laparoscopic surgery. A report of 2 cases.
Chan Louis YS, Yuen PM
J Reprod Med 2003;48(7): 569 - 571
16The effect of intra-abdominal pressure on the generation of 8-iso prostaglandin F2α during laparoscopy in rabbits
De Souza A, Wang CC, Chu NCY, Lam PM, Rogers MS
Hum Reprod 2003;18(10): 2181 - 2188
17Intrauterine Adhesions after Conservative and Surgical Management of Spontaneous Abortion.
Tam WH, Lau WC, Cheung LP, Yuen PM, Chung TKH
J Am Assoc Gyn Lap 2002;9(2): 182 - 185
18Patient-Controlled Sedation for Outpatient Thermal Balloon Endometrial Ablation.
Lok IH, Chan MTV, Tam WH, Leung PL, Yuen PM
J Am Assoc Gyn Lap 2002;9(4): 436 - 441
19Randomized double-masked comparison of radially expanding access device and conventional cutting tip trocar in laparoscopy.
Yim SF, Yuen PM
Obstet Gynecol 2001;97(3): 435 - 438
20Use of diclofenac as an analgesic in outpatient hysteroscopy: a randomized, double-blind, placebo-controlled study.
Tam WH, Yuen PM
Fertil Steril 2001;76(5): 1070 - 1072
21A randomised double-blind placebo-controlled trial of transcervical intrauterine local anaesthesia in outpatient hysteroscopy.
Lau WC, Tam WH, Lo KWK, Yuen PM
BJOG 2000;107(5): 610 - 613
22Complications of Laparoscopic Surgery for Benign Ovarian Cysts.
Lok IH, Sahota DS, Rogers MS, Yuen PM
J Am Assoc Gyn Lap 2000;7(4): 529 - 534
23Paracervical anaesthesia in outpatient hysteroscopy: a randomised double-blind placebo controlled trial.
Lau WC, Yuen PM
BJOG 2000;107(1): 143 - 144
24Small bowel herniation through subumbilical port site following laparoscopic surgery at the time of reversal of anesthesia
Leung TY, Yuen PM
Gynecol Obstet Inves 2000;49(3): 209 - 210
25The role of outpatient diagnostic hysteroscopy in the identifying anatomic pathology and histopathology in the endometrial cavity.
Lo KWK, Yuen PM
J Am Assoc Gyn Lap 2000;7(3): 381 - 385
26Ectopic pregnancy diagnosed by laparoscopic ultrasound scan.
Leung TY, Ng PS, Fung TY
Ultrasound Obst Gyn 1999;13(4): 281 - 282
27Mortality following Laparoscopic Surgery.
Lo KWK, Yuen PM
Gynecol Obstet Inves 1999;48(3): 203 - 204
28Paracervical anaesthesia in outpatient hysteroscopy: a randomised double-blind placebo-controlled trial.
Lau WC, Lo KWK, Tam WH, Yuen PM
BJOG 1999;106(4): 356 - 359
29Patient's acceptability to outpatient hysteroscopy.
Lau WC, Ho RYF, Tsang MK, Yuen PM
Gynecol Obstet Inves 1999;47(3): 191 - 193
30Hysteroscopic metroplasty under laparoscopic ultrasound guidance.
Lo KWK, Yuen PM
Acta Obstet Gyn Scan 1998;77: 580 - 581
31Intraoperative laparoscopic sonography improves pre-operative sonographic pathological characterisation of adnexal masses.
Yang WT, Yuen PM, Ho SSY, Leung TN, Metreweli C
J Ultras Med 1998;17(1): 53 - 61
32Laparoscopic adnexal ultrasonography: tecnhique in search of an indication.
Yang WT, Yuen PM
J Ultras Med 1998;17(5): 339 - 340
33Metabolic and inflammatory responses after laparoscopic and abdominal hysterectomy.
Yuen PM, Mak TWL, Yim SF, Ngan Kee WD, Lam CWK, Rogers MS, Chang AMZ
Am J Obstet Gynecol 1998;179(1): 1 - 5
34電視腹腔鏡術在子宮內膜異位症診治的應用
Yuen PM, Wong YF
Chin J Prac Gynecol Obstet 1997;13(6): 329 - 330
35A randomized prospective study of laparoscopy and laparotomy in the management of benign ovarian masses.
Yuen PM, Yu KM, Yip SK, Lau WC, Rogers MS, Chang AMZ
Am J Obstet Gynecol 1997;177(1): 109 - 114
36A review of laparoscopy and laparotomy in the management of tubal pregnancy.
Yuen PM, Rogers MS, Chang AMZ
Hong Kong Med J 1997;3(2): 153 - 157
37Complications of Laparoscopic Hysterectomy: a Literature Review.
Yuen PM
ELSA 1997;2(2): 36 - 40
38Laparoscopic management of adnexal mass during pregnancy.
Yuen PM, Chang AMZ
Acta Obstet Gyn Scan 1997;76: 173 - 176
39Controversies in laparoscopic management of ovarian tumours.
Yuen PM
ELSA 1996;1(4): 84 - 85
40Is laparoscopically-assisted vaginal hysterectomy associatied with low operative morbidity?
Yuen PM, Rogers MS
Aust NZ J Obstet Gyn 1996;36(1): 39 - 43
41Unexpected ovarian malignancy diagnosed after laparoscopic surgery.
Yuen PM, Leung TN
Aust NZ J Obstet Gyn 1996;36(1): 98 - 99
42A comparison of laparotomy and laparoscopy in the management of ovarian masses.
Yuen PM, Lo KWK, Rogers MS
J Gynecol S 1995;11(1): 19 - 25
43Adenomyosis following endometrial rollerball ablation.
Yuen PM
Aust NZ J Obstet Gyn 1995;35(3): 335 - 336
44Early incisional hernia following laparoscopic surgery.
Yuen PM
Aust NZ J Obstet Gyn 1995;35(2): 211 - 212
45The use of an Atad Ripener Device in the management of inferior epigastric artery injury during operative laparoscopy.
Yuen PM, Rogers MS
Acta Obstet Gyn Scan 1995;74(8): 645 - 646
46Transvaginal endoscopic oophorectomy.
Yuen PM
Am J Obstet Gynecol 1995;173(3): 976 - 977
47Case report: Laparoscopic removal of a retained surgical gauze after vaginal hysterectomy.
Yuen PM, Rogers MS, Chang AMZ
Eur J Obstet Gyn R B 1994;57(3): 209 - 210
48Combined laparoscopic and micro-laparotomy removal of benign cystic teratomata.
Yuen PM
BJOG 1994;101(7): 647 - 648
49Laparoscopic hysterectomy: do we need to remove the cervix?
Yuen PM, Rogers MS
Aust NZ J Obstet Gyn 1994;34(4): 464 - 466
50Laparoscopic management of ovarian masses - the initial experience and learning curve.
Yuen PM, Rogers MS
Aust NZ J Obstet Gyn 1994;34: 191 - 194
51Laparoscopic removal of ovarian cysts using a zipper storage bag.
Yuen PM, Rogers MS
Acta Obstet Gyn Scan 1994;73(10): 829 - 831
52Laparoscopic surgery in gynaecology.
Yuen PM
HK Pract 1994;16(1): 24 - 28
53Wound recurrence by implantation of a borderline ovarian tumour following laparoscopic removal.
Yuen PM
BJOG 1994;101(11): 1026 - 1027
54Laparoscopic removal of dermoid cysts using Endopouch.
Yuen PM, Rogers MS
Aust NZ J Obstet Gyn 1993;33(4): 397 - 399
55Endometrial Ablation - Conservative surgery for the treatment of menorrhagia.
Lau TK, Leung AKL
HK Pract 1991;13: 1737 - 1741
56Endometrium ablation for the treatment of menorrhageia.
Wong YF, Leung KL
Abroad Med 1991;18: 345 - 347
57Hysteroscopy - A 1990 update.
Lau TK, Leung AKL
HK Pract 1991;13: 1433 - 1436
58Recent advances in gynaecolgy-laparoscopic CO2 laser surgery.
Wong FWS
HK Pract 1991;13: 1422 - 1425
59Laparoscopy.
Mao KR, Li CY, Chang AMZ
HK Pract 1986;8(8): 1969 - 1974