CHAN Yiu Leung, David

Current Position:
Research Assistant Professor

Office Phone:
(852) 3505 3199


BSc (Ulster), MPhil (CUHK), DPhil (Oxon)
Certified Medical Technologist (American Medical Technologist, AMT)

Professor CHAN Yiu Leung David earned his bachelor degree in Biotechnology in Ulster University (UK) in 2002 and his MPhil in brain cancer research in The Chinese University of Hong Kong (CUHK) in 2006 respectively. In 2006, he was a Visiting Scholar in University of Pennsylvania to study reproductive cloning. He then obtained his DPhil in chromosome engineering from University of Oxford (UK) in 2011, supported by Clarendon Award and Hong Kong China Oxford scholarships. Professor CHAN had his post-doctoral training in CUHK briefly and then he was trained and practiced in embryology and andrology in University of Hong Kong (HKU), Queen Mary Hospital (QMH) for four and a half years. He joined the Department of Obstetrics and Gynaecology, CUHK in August 2016 and was appointed as Research Assistant Professor in the reproductive medicine team of CUHK.

1Influence of the period of abstinence on semen quality in a patient with systemic lupus erythematosus – A case report and review of the literature
Waters THB, Chan CPS, Li TC, Chan DYL
Case Rep Rheumatol. 2020 Mar 7;2020:9296858
2Multigene human artificial chromosome vector delivery with herpes simplex virus 1 amplicons
Chan DYL, Moralli D, Wheatley L, Jankowska JD, Monaco ZL
Exp Cell Res. 2020 Mar 15;388(2):111840 (5 pages)
3The effects of daily meteorological perturbation on pregnancy outcome: Follow-up of a cohort of young women undergoing IVF treatment
Zhao M, Zhang H, Waters THB, Chung JPW, Li TC, Chan DYL
Environ Health. 2019 Nov 28;18(1):103, 14pages
4A double-blinded, randomized placebo-controlled trial on the effect of traditional Chinese medicine formula Wuzi Yanzong pill on improving semen qualities in men with suboptimal parameters
Zhao M, Chan CPS, Cheung CWC, Alqawasmeh O, Wang CC, Wu JCY, Lin ZX, Li TC, Chung JPW, Mak JSM, Law SM, Chan DYL
Trials. 2019 Aug 29;20(1):540 (7 pages)
5Maternal β-HCG concentrations in early IVF pregnancy: association with the embryo development stage of blastocysts
Zhu W, Yeung QSY, Chan DYL, Chi L, Huang J, Wang Q, Chung JPW, Li TC
Reprod Biomed Online. 2019 May;38(5):683-690
6Mitochondria Manipulation in Oocytes: A Mini-Review
Zhao M, Li TC, Chan DYL
Int J Obstet Gynaecol Stud. 2017 1(1) :1-5
7Comparative analysis of single-cell parallel sequencing approaches in oocyte application
Qian Y, Liao J, Suen AHC, Lee AWT, Chung CHS, Tang NLS, Chow KL, Cao Q, Yip YL, Leung TY, Chan WY, Chan DYL, Li TC, Lee TL
Int J Biochem Cell Biol. 2019 Feb;107:1-5
8Comparison of DNA fragmentation levels in spermatozoa with different sex chromosome complements
Shi X, Chan DYL, Zhao MP, Chan CPS, Huang J, Li TC
Reprod Biomed Online. 2019 Jan;38(1):56-65
9Lifestyle and demographic factors associated with human semen quality and sperm function
Shi X, Chan CPS, Waters T, Chi L, Chan DYL, Li TC
Syst Biol Reprod Med. 2018 Oct;64(5):358-367
10The Therapeutic Effects of a Traditional Chinese Medicine Formula Wuzi Yanzong Pill for the Treatment of Oligoasthenozoospermia: A Meta-Analysis of Randomized Controlled Trials
Zhao M, Shi X, Kong GWS, Wang CC, Wu JCY, Lin Z, Li TC, Chan DYL
Evidence-Based Complementary and Alternative Medicine. 2018;2018:10. doi: 10.1155/2018/2968025.
11Mitochondria Manipulation in Oocytes: A Mini-Review.
Ming Peng Zhao TCL, Chan DYL
Int J Obstet Gynaecol Study. 2017;1(1).
12Comparison of the external physical damages between laser-assisted and mechanical immobilized human sperm using scanning electronic microscopy.
Chan DYL, Li TC.
PloS one. 2017;12(11):e0188504. Epub 2017/11/28. doi: 10.1371/journal.pone.0188504. PubMed PMID: 29176855.
13Human varicella zoster virus is not present in the semen of a man affected by chickenpox during the in vitro fertilisation of his wife.
Chan DYL, Lam KKW, Lau EYL, Yeung WSB, Ng EHY
Andrologia. 2017. Epub 2017/07/04. doi: 10.1111/and.12822. PubMed PMID: 28670753.
14Noncoding Centromeric RNA Expression Impairs Chromosome Stability in Human and Murine Stem Cells
Chan DYL, Moralli D, Khoja S, Monaco ZL
Disease Markers. 2017;2017:8. doi: 10.1155/2017/7506976.